What is it about?

Polyphenols are responsible for the number of pharmacological effects of Bergenia. UPLC-DAD-QqQ-MS and LC-DAD-ESI-QTOF-MS were used for the rapid profiling of phenolic compounds, mainly hydrolysable tannins. Green leaves consisted of 55% ellagitannins, 29% gallic acid derivatives and 11% flavonoids, with the remaining gallic acid, arbutin, bergenin and caffeoyl quinic acid. In fermented leaves, 31% of gallic acid was found, followed with 28% ellagitannins, 18% gallic acid derivatives and 18% flavonoids, with the remaining caffeoyl quinic acid, bergenin and arbutin. Tellimagrandin I, pedunculagin, caffeoyl quinic acid, monogalloyl quinic acid, 1-O-galloylglucose and 1,2,6-tri-O-galloylglucose were identified for the very first time.

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Why is it important?

It is important to highlight that this is the first study to report the compounds tellimagrandin I, pedunculagin, caffeoyl quinic acid, monogalloyl quinic acid, 1- O-galloylglucose and 1,2,6-tri-O-galloylglucose in B. crassifolia leaves.

Perspectives

The phenolic profile of green leaves was different from fermented leaves and associated with the processes during fermentation.

Professor Alexander N. Shikov
Saint-Petersburg State Chemical Pharmaceutical University

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This page is a summary of: Rapid profiling of phenolic compounds of green and fermented Bergenia crassifolia L. leaves by UPLC-DAD-QqQ-MS and HPLC-DAD-ESI-QTOF-MS, Natural Product Research, June 2014, Taylor & Francis,
DOI: 10.1080/14786419.2014.923999.
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