What is it about?
Trypanosomiasis is an important disease where new drugs are needed. PPIs are safe drugs that can be used in cases of trypanosomiasis without current treatment, as occurs in pregnant women. Here, we show results to support the use of rabeprazole as a potential drug in a new treatment for trypanosomiasis.
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Why is it important?
This proposal could be used to develop treatments in cases where the first line drugs can not be used.
Perspectives
To demonstrate clinically the effectiveness of our proposal.
Dr Gabriel Lopez-Velazquez
Instituto Nacional de Pediatria
Read the Original
This page is a summary of: Repurposing of rabeprazole as an anti-Trypanosoma cruzi drug that targets cellular triosephosphate isomerase, Journal of Enzyme Inhibition and Medicinal Chemistry, July 2023, Taylor & Francis,
DOI: 10.1080/14756366.2023.2231169.
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