Surfactant–copper(II) Schiff base complexes: synthesis, structural investigation, DNA interaction, docking studies, and cytotoxic activity

Jagadeesan Lakshmipraba, Sankaralingam Arunachalam, Rajadurai Vijay Solomon, Ponnambalam Venuvanalingam, Anvarbatcha Riyasdeen, Rajakumar Dhivya, Mohammad Abdulkader Akbarsha
  • Journal of Biomolecular Structure and Dynamics, May 2014, Taylor & Francis
  • DOI: 10.1080/07391102.2014.918523

What is it about?

Surfactant metal complex behaves different from metal complex when it comes for biological activity. Here we studied how surfactant–copper(II) Schiff base complexes interact with DNA using multispectroscopic techniques along with molecular docking technique.

Why is it important?

Understanding the structure and property of surfactant metal complexes for their biological activity is very important. Here spectroscopic, molecular docking, cytotoxic studies have been attempted to achieve this goal.

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http://dx.doi.org/10.1080/07391102.2014.918523

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