What is it about?

This paper reviews the use of analgesics in acute pain. It focus on the frequent necessity to combine two or more analgesics. It extensively presents the scientific data obtained with the use of a newly registered pharmaceutical specialty, which is the fixed dose combination of a weak opioid and a very well know NSAID

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Why is it important?

Frequently chronic pain patients are difficult to treat. One single drug is not always enough to produce acceptable analgesic effects. This paper is presenting to the physicians a new product, a combination of two analgesics, that could result useful to obtain better analgesia with low side effects.


This publication should represent a good lecture and guidance for all the physicians involved in pain management. Most of the analgesic have side effects, hence they cannot be used for long time or at high dosages without fearing for damages to the patients in treatment. Frequently the possibility to have two analgesics combined in an ideal dosages, acting in two different side of action, may result very useful.

Professor Giustino Varrassi
Paolo Procacci Foundation

Read the Original

This page is a summary of: Multimodal analgesia in moderate-to-severe pain: a role for a new fixed combination of dexketoprofen and tramadol, Current Medical Research and Opinion, April 2017, Taylor & Francis, DOI: 10.1080/03007995.2017.1310092.
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