What is it about?
Purpose of present study was to develop eight formulations of chlorpheniramine (CPM) niosomes according to 23 factorial design, characterize on the basis of various evaluation tests, i.e. in vitro drug release, SEM, FTIR, TGA and release kinetics, optimize the eight formulation on the basis in vitro drug release data, formulate gel of optimized dispersion, and to perform in vivo and histopathological study using gel of optimized dispersion on rabbits.
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Why is it important?
Niosomal gel of CPM ensured successful development using suitable combination of non-ionic surfactants, and effective loading of drug for targeted delivery of drug.
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This page is a summary of: Formulation and evaluation of niosomes-based chlorpheniramine gel for the treatment of mild to moderate skin allergy, Journal of Experimental Nanoscience, July 2022, Taylor & Francis, DOI: 10.1080/17458080.2022.2094915.
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