What is it about?

Enthusiasm for use of nanoparticles in human medicine has been running high. This article reviews how metal nanoparticles might promise benefit, but also points out the possibility of adverse reactions to metal nanoparticles.

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Why is it important?

Recognition of adverse reactions to metals has often lagged decades behind the introduction of metals into common use. Examples include the use of tetraethyl lead as an additive in gasoline, use of lead oxide in house paint, and gadolinium as a contrast agent in MRI examinations. Similar lags could occur with the use of metal nanoparticles.

Perspectives

Enthusiasm for use of metal nanoparticles must be balanced against the possibility of adverse effects. Many of the adverse effects would not be detected in studies of cultured cells alone.

Dr John K. Crane
University at Buffalo

Read the Original

This page is a summary of: Metal Nanoparticles in Infection and Immunity, Immunological Investigations, June 2020, Taylor & Francis, DOI: 10.1080/08820139.2020.1776724.
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