What is it about?

High-altitude lakes like Lake Nam Co in Tibet are extreme environments, with cold temperatures, low nutrients, and intense UV radiation. These conditions make them a fascinating but largely unexplored habitat for RNA viruses. In this study, we conducted the first large-scale genetic analysis of RNA viruses in Lake Nam Co, identifying 742 different virus species—many of them completely new to science. Some of these viruses may infect bacteria, challenging the common idea that RNA viruses mainly target animals and plants. We also found genetic clues suggesting that certain viruses might influence how their hosts produce energy, which could be important in such harsh environments. Our findings expand our understanding of viral diversity and evolution, showing that extreme ecosystems like this lake can reveal surprising biological discoveries, especially in the face of climate change.

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Why is it important?

Our research provides the first in-depth look at RNA viruses in Lake Nam Co on Tibetan Plateau. By uncovering hundreds of previously unknown viruses—some with unique evolutionary traits and potential bacterial hosts—this study challenges conventional assumptions about RNA virus diversity and ecology. In a time when climate change is rapidly altering fragile ecosystems, understanding how viruses interact with their environment is more crucial than ever. Our work not only expands scientific knowledge of viral evolution but also highlights the role of extreme habitats as reservoirs of undiscovered biodiversity, with potential implications for global ecosystem stability.

Perspectives

Having the opportunity to be part of the exploration of RNA viruses in Tibetan Plateau lakes is truly invaluable. It is my privilege and honor to work alongside the dedicated authors who have put tremendous effort into this study. I hope our hard work can provide new perspectives on the diversity and evolutionary characteristics of viruses.

Qiang Zheng
Xiamen University

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This page is a summary of: Uncovering the hidden RNA virus diversity in Lake Nam Co: Evolutionary insights from an extreme high-altitude environment, Proceedings of the National Academy of Sciences, February 2025, Proceedings of the National Academy of Sciences,
DOI: 10.1073/pnas.2420162122.
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