What is it about?
The discovery and role of molecular chaperones in health and disease
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Why is it important?
These chaperone proteins are multi-functional in various cellular compartments and are stress inducible to impact homeostasis and disease progression.
Perspectives
A summary of this research area in the last 5 decades.
Amy Lee
University of Southern California
Read the Original
This page is a summary of: Stress-induced translocation of the endoplasmic reticulum chaperone GRP78/BiP and its impact on human disease and therapy, Proceedings of the National Academy of Sciences, July 2025, Proceedings of the National Academy of Sciences,
DOI: 10.1073/pnas.2412246122.
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