What is it about?
We found that temperature memory in neurons adjusts the gut fat storages for acclimating to the environmental temperature. We found that neural circuits that circumnavigate the body from the head to the tail to back to the head act on the gut to regulate temperature acclimation by changing the gut fat amount.
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Why is it important?
Our result leads to the breakdown of fat retained in the intestine, and it is thought that when cultivated at high temperatures, the gut fat amount is reduced, making it less able to tolerate lower temperature.
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This page is a summary of: Head-tail-head neural wiring underlies gut fat storage in
Caenorhabditis elegans
temperature acclimation, Proceedings of the National Academy of Sciences, August 2022, Proceedings of the National Academy of Sciences,
DOI: 10.1073/pnas.2203121119.
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