What is it about?
The study looks at how neuronal cells talk to one another, in a region of the brain’s hippocampus called the CA3. This brain region has long been thought to be involved in memory formation as well as enabling us to learn new tasks, yet we still don’t know exactly how. In this research, we explore how the communication between cells may contribute to these processes.
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Why is it important?
Understanding how the brain works is crucial for enabling us to better treat neurological disorders. Due to its role in memory formation, the hippocampus is a key target for dementia-related diseases like Alzheimer’s Disease. Therefore, unravelling how neurons in this brain region communicate with one another in a healthy setting can help us to understand why things go wrong in disease, and provide us with new ways to target potential therapies.
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This page is a summary of: Structure and function of the hippocampal CA3 module, Proceedings of the National Academy of Sciences, January 2024, Proceedings of the National Academy of Sciences,
DOI: 10.1073/pnas.2312281120.
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