What is it about?
Although turnover of sex chromosomes is very common in many vertebrate lineages, the transition process is still elusive. We studied the sex-determining region of 12 congeneric fish species of Takifugu pufferfish that compose an important model for the study of genomics and sex determination.
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Why is it important?
We found that while nine species retained their ancestral sex-determining region (SDR), three species had acquired derived SDRs. Although the derived SDRs resided in three different chromosomes, they harbored a shared supergene flanked by two putative transposable elements. The results highlight the underestimated role of a mobile supergene in turnover of sex chromosomes in vertebrates.
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This page is a summary of: Repeated translocation of a supergene underlying rapid sex chromosome turnover in
pufferfish, Proceedings of the National Academy of Sciences, June 2022, Proceedings of the National Academy of Sciences,
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