What is it about?
Viral vectors are now an indispensable tool in advanced medicine, including gene therapy, cancer treatment, and vaccine development. In order to maximize their usefulness while minimizing potential risks, methods to completely control their multiplication are required. Attaching a simple switch to viral vectors to completely control their proliferation is ideal, but has been considered impossible. In this study, an innovative solution to this problem is presented, and an excellent example of its success is shown.
Photo by Elena Mozhvilo on Unsplash
Why is it important?
The ability to control the growth of viral vectors with light will allow us to control the growth of viral vectors spatiotemporally (when and where they are needed (organs, tissues, etc.)). In this study, the control has been achieved with a simple blue diode irradiation device.
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This page is a summary of: Photocontrollable mononegaviruses, Proceedings of the National Academy of Sciences, May 2019, Proceedings of the National Academy of Sciences, DOI: 10.1073/pnas.1906531116.
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