What is it about?
This paper introduces a laboratory-based x-ray microscope for 3D imaging of soft tissue biopsies with micron and sub-micron resolution. The microscope uses intensity-modulation masks to access transmission, refraction and dark-field contrast channels. We demonstrated that the resolution of the microscope does not depend on source size or detector pixel pitch, but only on the mask aperture width.
Photo by Mathew Schwartz on Unsplash
Why is it important?
This result breaks the link between the factors that traditionally determine spatial resolution in x-ray images (focal spot, detector pixel pitch) and the resolution level actually achieved in an image: this is pivotal for the development of a multi-resolution system where it would be possible to navigate across different sample scales by changing the mask aperture without other modifications.
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This page is a summary of: A laboratory-based, low-energy, multi-modal x-ray microscope with user-defined resolution, Applied Physics Letters, June 2022, American Institute of Physics, DOI: 10.1063/5.0082968.
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