What is it about?
Both potassium depletion and renal ablation result in proximal tubule hypertrophy and the angiotensin II type 1 (AT1) receptor localization in rat proximal tubules.
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Why is it important?
It is possible that the AT1 receptor intracellular distribution is modulated by potassium depletion in proximal tubular cells of 5/6 nephrectomized rats.
Perspectives
In normal rats and those subjected to renal ablation, the immunocytochemical data provide intracellular proximal tubule AT1 receptor density after potassium depletion.
Dr Masoud Ghorbani
Pasteur Institute of Iran
Read the Original
This page is a summary of: Effect of potassium depletion on proximal tubule AT1 receptor localization in normal and remnant rat kidney, Kidney International, November 2001, Elsevier,
DOI: 10.1046/j.1523-1755.2001.00992.x.
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