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Why is it important?
The synthetic methodology described here for the synthesis of orotidine overcomes many of the issues faced in the past. Specifically it allows for the correct isomer to be produced without any side reactions, in a very short time with high efficiency.
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This page is a summary of: Synthesis of orotidine by intramolecular nucleosidation, Chemical Communications, January 2015, Royal Society of Chemistry,
DOI: 10.1039/c5cc00111k.
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