What is it about?

Provides a new chemical scaffold a lead compound for the treatment of HCC.

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Why is it important?

HCC is one of the leading cancer, and currently no effective medication is available.

Perspectives

Toward the optimization as a drug candidate for clinical testing.

Prof. Yijun Chen
China Pharmaceutical University

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This page is a summary of: Novel 2-phenyloxypyrimidine derivative induces apoptosis and autophagy via inhibiting PI3K pathway and activating MAPK/ERK signaling in hepatocellular carcinoma cells, Scientific Reports, July 2018, Springer Science + Business Media,
DOI: 10.1038/s41598-018-29199-8.
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