What is it about?
Genetic transcription requires the melting of DNA at promoter regions. The promoter is a genomic sequence where transcription machinery orchestrated. Promoter delineation from other genomic sequences is a challenging task. This paper reports the application of DNA stability based tool "PromPredict" for the identification of promoters.
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Why is it important?
The work is significant in the filed of promoter biology. The algorithm utilized for this can be used for annotation of genomic regions
Perspectives
The tool reported in this paper can help the researchers working in the field of promoter biology.
Dr Venakata Rajesh Yella
Koneru Lakshmaiah Education Foundation
Read the Original
This page is a summary of: Identification of putative promoters in 48 eukaryotic genomes on the basis of DNA free energy, Scientific Reports, March 2018, Springer Science + Business Media,
DOI: 10.1038/s41598-018-22129-8.
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