What is it about?

This work was designed to understand actual molecular and immunological pathways are motivated by indoleamine 2,3 dioxygenase enzyme.

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Why is it important?

The importance of this work to explore tumorigenesis specific pathways that mediated by IDO enzyme to specify a new chemotherapeutic target, which could help to develop new therapeutic strategy

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This page is a summary of: 1-Methyl-D-tryptophan Reduces Tumor CD133+ cells, Wnt/β-catenin and NF-κβp65 while Enhances Lymphocytes NF-κβ2, STAT3, and STAT4 Pathways in Murine Pancreatic Adenocarcinoma, Scientific Reports, June 2018, Springer Science + Business Media,
DOI: 10.1038/s41598-018-28238-8.
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