Publication
Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 3: Development of a One-Pot Formylation–Cyclization Sequence to the Diaminopyrimidine Core
Kallol Basu, Dan Lehnherr, Gary E. Martin, Richard A. Desmond, Yu-hong Lam, Feng Peng, John Y. L. Chung, Rebecca A. Arvary, Michael A. Zompa, Si-Wei Zhang, Jinchu Liu, Zachary E. X. Dance, Patrick Larpent, Ryan D. Cohen, Francisco J. Guzman, Nicholas J. Rogus, Michael J. Di Maso, Hong Ren, Kevin M. Maloney
Organic Process Research & Development, October 2020, American Chemical Society (ACS)
DOI: 10.1021/acs.oprd.0c00246