What is it about?
New oral co-amorphous systems of an anthelmintic drug flubendazole are being investigated as an alternative to the commercial form. Improved release of flubendazole due to co-amorphization and complexation
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Why is it important?
Rarely are the molecular causes of high supersaturation investigated. In this paper, we investigate the cause of stable and high supersaturation for co-amorphous systems
Perspectives
Use of these systems as an alternative to the commercial form to improve pharmaceutical properties, repurpose for cancer treatment and circumvent existing patents
Nikita Vasilev
Institute of Solution Chemistry of RAS
Read the Original
This page is a summary of: Influence of Co-amorphization on the Physical Stability and Dissolution Performance of an Anthelmintic Drug Flubendazole, Molecular Pharmaceutics, February 2023, American Chemical Society (ACS),
DOI: 10.1021/acs.molpharmaceut.2c00873.
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