Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity

Sreekanth Kokkonda, Xiaoyi Deng, Karen L. White, Jose M. Coteron, Maria Marco, Laura de las Heras, John White, Farah El Mazouni, Diana R. Tomchick, Krishne Manjalanagara, Kakali Rani Rudra, Gong Chen, Julia Morizzi, Eileen Ryan, Werner Kaminsky, Didier Leroy, María Santos Martínez-Martínez, Maria Belen Jimenez-Diaz, Santiago Ferrer Bazaga, Iñigo Angulo-Barturen, David Waterson, Jeremy N. Burrows, Dave Matthews, Susan A. Charman, Margaret A. Phillips, Pradipsinh K. Rathod
  • Journal of Medicinal Chemistry, May 2016, American Chemical Society (ACS)
  • DOI: 10.1021/acs.jmedchem.6b00275

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http://dx.doi.org/10.1021/acs.jmedchem.6b00275

The following have contributed to this page: Professor Diana R. Tomchick