What is it about?
Novel ELPs, cyclo[FPGVG]n (n = 3–5) demonstrated stronger coacervation capacity.
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Why is it important?
Because of strong coacervation potency of cyclo[FPGVG]n (n = 3–5) with low concentration requirements, the findings of this study could be useful to elucidate the coacervation mechanisms of short ELPs.
Perspectives
The cyclization technique can be expected to contribute to the application of short coacervatable ELPs to generate novel peptide-based functional biomaterials.
Prof Takeru Nose
Kyushu Daigaku
Read the Original
This page is a summary of: Enhancement of Self-Aggregation Properties of Linear Elastin-Derived Short Peptides by Simple Cyclization: Strong Self-Aggregation Properties of Cyclo[FPGVG]n, Consisting Only of Natural Amino Acids, Biomacromolecules, June 2018, American Chemical Society (ACS),
DOI: 10.1021/acs.biomac.8b00353.
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