Mechanism of action of narcolepsy medications

What is it about?

The medications used to treat narcolepsy are targeted towards alleviating symptoms such as excessive sleepiness and cataplexy. The cause of this neurological sleep disorder is still not completely clear, though a destruction of hypocretin/orexin neurons has been implicated. In this paper, we seek to review the mechanisms of action behind these classes of drugs. Appropriate clinical strategies will be discussed, including specific combinations of medications that have been shown to be effective.

Featured Image