What is it about?
Reactive oxygen species or free radicals cause mitochondrial mutations in the lung of smokers and the elderly.
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Why is it important?
Smoking increases the amount of mitochondrial DNA mutations and oxidative damage in human lung.
Perspectives
To avoid exposure to cigarette smoke can help maintain the integrity of mitochondrial DNA in the lung.
Professor and Director Yau-Huei Wei
Changhua Christian Hospital
Read the Original
This page is a summary of: Aging- and smoking-associated alteration in the relative content of mitochondrial DNA in human lung, FEBS Letters, December 1998, Wiley,
DOI: 10.1016/s0014-5793(98)01564-6.
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