What is it about?
Our review aims to convey a broad and complex interplay between the frequently examined cells of the mesenchymal lineage -specifically adipocytes and osteoblasts- but to broaden this to include chondrocytes , as well as hematopoietic-derived osteoclasts.
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Why is it important?
In seeking to build on known interplay between diverse skeletal cell populations, we ask how interactions between a multitude of cells might be attenuated with non-pharmacologic, exercise and dietary based interventions for aging related conditions like osteoporosis and osteoarthritis.
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This page is a summary of: Exercise to Mend Aged-tissue Crosstalk in Bone Targeting Osteoporosis & Osteoarthritis, Seminars in Cell and Developmental Biology, September 2021, Elsevier, DOI: 10.1016/j.semcdb.2021.08.011.
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Funding / Marrow Adipose Compartment Physiology in Caloric Restriction and Aging
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