Bone Health in Osteosarcoma and Ewing's Sarcoma Survivors: A Scoping Review

What is it about?

In this scoping review, the authors aimed to investigate the bone health status of long-term survivors of osteosarcoma and Ewing's sarcoma (OS/ES). They found that more than 50% of these survivors have a bone mass deficit, with a higher prevalence of osteoporosis and osteopenia compared to other childhood cancer survivors. However, the available data were insufficient to determine if these survivors face an increased risk of fractures. The study highlights the knowledge gap in understanding the bone health status of OS/ES survivors and emphasizes the need for further research to assess the potential association between bone mass deficits and fracture risk. [Some of the content on this page has been created by AI]

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Why is it important?

This research is important because it highlights the knowledge gap in understanding the bone health status of long-term survivors of osteosarcoma and Ewing's sarcoma. These survivors may face an increased risk of fractures due to bone mass deficits, which can negatively impact their quality of life. Key Takeaways: 1. A relatively large knowledge gap exists in our understanding of bone health status in OS/ES survivors. 2. The prevalence of osteoporosis and osteopenia may be higher in long-term OS/ES survivors than in other childhood cancer survivors. 3. There is an unappreciated knowledge gap in our understanding of bone health status in those survivors, and more research is needed to determine if these survivors face an increased risk of fractures.