What is it about?
In this study, phytochemical screening, antimicrobial and antifungal activities of leaves extract and partitions were evaluated. Phytochemical screening tests indicated the presence of flavonoids, terpenoids, phenols, sugar, steroids, triterpenoids, and tannins compounds. No alkaloids or nitrogenated compounds were found. Antioxidant, antimicrobial and antifungal activities were tested.
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Why is it important?
The extract and partitions from the B. laevifolia leaves demonstrated relevant scavenging free radical DPPH effect. The crude extract and partitions inhibit bacteria growth with minimum inhibitory concentrations (MIC) below 400 mg L-1 for most oral microorganisms tested. Meanwhile, the antifungal activity proved to be very promising for the ethanolic extract and partitions (31-375 μg mL-1) against all yeasts tested. The antimicrobial activities results are very promising since the ethanol extract and the more active n-buthanol partition showed great selectivity (0.9-1.2; 0.1-0.7, respectively) against microorganisms and relatively low toxicity to Vero cells.
Perspectives
The biological activity results and MS analysis for the B.laevifolia leaves revealed that they have efficient antimicrobial agents, and contributed to the chemical and biological knowledge of the genus.
Dr. FRANCISCO JOSÉ TÔRRES DE AQUINO
Universidade Federal de Uberlandia
Read the Original
This page is a summary of: Antimicrobial activity, cytotoxicity and selectivity index of Banisteriopsis laevifolia (A. Juss.) B. Gates leaves, Industrial Crops and Products, December 2016, Elsevier,
DOI: 10.1016/j.indcrop.2016.08.016.
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