What is it about?
Cancer is one of the top causes of sickness and mortality throughout the world [1,2]. It is one of the non-communicable diseases that cause this. Recent evidence released by the World Health Organization (WHO) suggests that cancer is the second leading cause of death in the world, having been responsible for the passing of 10 million people in the year 2020 [2,3]. The harsh repercussions of cancer treatments have a significant psychological and financial impact on nations that are afflicted by the disease. This is in addition to the growing death rates caused by the disease [1].
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Why is it important?
Therefore, as was pointed out in the previous paragraph, bacteriocins generated by lactic acid bacteria are an essential component of human biology for maintaining good health. Therefore, the purpose of this study is to provide an in-depth analysis of the recent breakthroughs and potential future technical advancements of significant bacteriocins that are produced by lactic acid bacteria, how these bacteriocins function, and how these bacteriocins may be utilized as an anti-cancer agent. When bacteriocins are used as an anticancer factor, they are subject to several key limits and limitations, which are brought to light in the present review.
Perspectives
LAB is a group of gram-positive bacteria that can be differentiated from one another using a wide range of morphological, microscopic, and biochemical tests [14]. The structure of the cell, the properties of glucose fermentation, the ability to utilize sugar, and the temperature ranges that are optimal for growth are all investigated in these tests [18]. Because of this, Lactobacillus, Pediococcus, Leuconostoc and Lactococcus comprise the core group of four genera. The recent use of molecular biological techniques has resulted in a rise in the number of genera. Some examples of bacteria are as follows: Aerococcus, Alloiococcus, Carnobacterium, Dolosigranulum, Enterococcus, Lactosphaera, Melissococcus, Oenococcus, Sporolactobacillus, Tetragenococcus, Vagococcus, and Weissella
Prof. Dr. Alaa Kareem Niamah
University of Basrah
Read the Original
This page is a summary of: Emerging lactic acid bacteria bacteriocins as anti-cancer and anti-tumor agents for human health, Heliyon, September 2024, Elsevier,
DOI: 10.1016/j.heliyon.2024.e37054.
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