Featured Image
Why is it important?
Repeated exposure of LPS causes corticosteroid-insensitive airway inflammation in vivo, and the corticosteroid-resistance induced by LPS is partly mediated through the activation of PI3Kδ, resulting in decreased levels of HDAC2 and Nrf2.
Perspectives
The mouse model we describe with repeated LPS exposure may prove to be a useful in vivo model to assess the effects of novel therapies.
Dr Yasuo Kizawa
Nihon University
Read the Original
This page is a summary of: Repeated lipopolysaccharide exposure causes corticosteroid insensitive airway inflammation via activation of phosphoinositide-3-kinase δ pathway, Biochemistry and Biophysics Reports, September 2016, Elsevier,
DOI: 10.1016/j.bbrep.2016.07.020.
You can read the full text:
Contributors
The following have contributed to this page
