What is it about?
For the first time no-carrier-added (nca) 209,210At radionuclides were produced by heavy ion (7Li) activation of lead nitrate target. Astatine was separated from the bulk target by three different approaches, by aqueous biphasic system (ABS), liquid liquid extraction (LLX) using liquid cation exchanger, HDEHP (di-2- ethylhexyl phosphoric acid), and solid liquid extraction system (SLX) using cation exchange resin Dowex-50.
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Why is it important?
For the first time At-209 and At-210 was produced by heavy ion (Li-7) activation. Also At showed different oxidation states unlike its lower homologue At, therefore new chemistry of astatine is concluded.
Perspectives
At-211 is believed to be one of the most important therapeutic radionuclide in bear future. This paper will help to understand the properties of At which will be helpful to design therapeutic strategies.
Professor Susanta Lahiri
Saha Institute of Nuclear Physics
Read the Original
This page is a summary of: Production and separation of Astatine Radionuclides: Some new addition to Astatine Chemistry, Applied Radiation and Isotopes, May 2008, Elsevier,
DOI: 10.1016/j.apradiso.2007.12.005.
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