Unilateral pedicle screw fixation for two-level degenerative disorders of spine

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Our meta-analysis establishes the immediate safety and significant lesser operative period of unilateral pedicle screw fixation in lumbar fusion. However, due to lack of evidence on complications like cage subsidence and adjacent segment disease, unilateral pedicle screw fixation cannot be recommended as an alternative to bilateral pedicle screw fixation for two-level degenerative spinal disease. Our analysis established the lacunae in literature for high-quality evidence on the subject hence we recommend further large multicentre studies with longer follow-up to arrive at a conclusion.

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