What is it about?

Thymoquinone (TQ) is a secondary metabolite found in abundance in very few plant species including Nigella sativa L., Monarda fistulosa L., Thymus vulgaris L. and Satureja montana L. Preclinical pharmacological studies have shown that TQ has many biological activities, such as anti-inflammatory, antioxidant and anticancer.

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Why is it important?

Both in vivo and in vitro experiments have shown that TQ acts as an antitumor agent by altering cell cycle progression, inhibiting cell proliferation, stimulating apoptosis, inhibiting angiogenesis, reducing metastasis and affecting autophagy.

Perspectives

The possibilities of success for this compound in human medicine should be further explored through clinical trials.

habilitated doctor, chemist Monica BUTNARIU
Life Sciences University "King Michael I" from Timisoara, 300645, Calea Aradului 119, Timis, Romania

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This page is a summary of: The effects of thymoquinone on pancreatic cancer: Evidence from preclinical studies, Biomedicine & Pharmacotherapy, September 2022, Elsevier, DOI: 10.1016/j.biopha.2022.113364.
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