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In type II diabetes, sitagliptin should be used combined with metformin or pioglitazone to decrease the risk of pancreatitis.

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This page is a summary of: Effect of metformin and pioglitazone on β-catenin and biochemical markers in sitagliptin-induced pancreatitis in diabetic rats, International Journal of Diabetes in Developing Countries, January 2015, Springer Science + Business Media,
DOI: 10.1007/s13410-014-0278-8.
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