What is it about?
The importance of thrombophilias in eye diseases is not determined. Family history of venous thromboembolism is more related to genetic than non-genetic factors. We have for the first time determined whether genetic factors involved in venous thromboembolism also are important for development of retinal vein or artery occlusion and also glaucoma
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Why is it important?
We do not find any association between family history of venous thromboembolism and retinal vein or artery thrombosis or glaucoma. The genetic of these eye diseases are thus completely unrelated to factors involved in venous thromboembolism. Determining major thrombophilias in patients with retinal vascular occlusions is therefore not relevant.
Perspectives
The present paper clearly shows that the etiology of retinal vein and artery occlusion is different from venous thromboembolism. Thus, retinal vascular occlusions is not a manifestation of major thrombophilias. Other factors should be looked for instead. Moreover, genetic vascular factors involved in venous thromboembolism are completely unrelated to glaucoma.
Professor, MD, PhD Bengt Zöller
Lunds Universitet
Read the Original
This page is a summary of: Venous thromboembolism does not share familial susceptibility with retinal vascular occlusion or glaucoma: a nationwide family study, Journal of Thrombosis and Thrombolysis, June 2016, Springer Science + Business Media,
DOI: 10.1007/s11239-016-1387-7.
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