What is it about?
Transformation of an angulated and polygonalnormal oral squamous cell into a keratinized narrow strip or ribbon-like flat projection results in what is called a keratinized strap cell (KSC). Nuclear pleomorphism in keratinized strap cells was observed to be narrow spindle, rod, and bar-shaped and to resemble Anitschkowcells. From the nature of the staining, the structural peculiarity, and the resemblance to Anitschkow cells, KSC, a rarely observed oral cytological atypia, were renamed as keratinized strap (Anitschkow) (KSC-A) cells.
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Why is it important?
Rare occurrence, cellular keratinization, nuclear pleomorphism, hyperchromasia, and increased N/C ratios for KSC-A in oral carcinoma, for both sexes, indicate a state of malignancy.
Perspectives
Extra cardio-vascular occurrence of KSC-As is considered to be a rare Finding in oral oncopathology. It has practical value for early detection and diagnosis of oral squamous cell carcinoma patients.
Dr ABHIMANYU MOHANTA
Utkal University
Read the Original
This page is a summary of: Keratinized strap cells: a rare cytological atypia resembles Anitschkow cells, in human oral neoplasm, International Journal of Clinical Oncology, July 2015, Springer Science + Business Media,
DOI: 10.1007/s10147-015-0865-9.
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