Summary of​ clinical trials investigating cell transplantation for intervertebral disc repair

What is it about?

A variety of trials have been performed or are on-going trying to use cell transplantation for restoring intervertebral disc and/or alleviating low back pain. This paper gives an up-to-date overview of all these studies and examines​ their study design, products, and outcomes.

Featured Image

Why is it important?

Cell transplantation for intervertebral disc repair is a rather new but promising field of research, providing a new therapy for still uncurable intervertebral disc degeneration. In-human studies are however still small in numbers, relatively​ small in size, and are differently designed. This review paper aims to update the readers on the differences in design, product, and their outcomes, to identify promising outcomes and shortcomings or questions that should be addressed by future studies.