What is it about?

In light of this literature, based on the hypothesis that the treatment model of therapeutic pulsed ultrasound (TPU) and vitamin C, which is known to be an antioxidant, and selenium on blood muscle tissue can be successful, this study was the first attempt to investigate the effects of these applications in the retrospective repair of experimental muscle injury in rats.

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Why is it important?

In conclusion, this current study has shown that in addition to ultrasound therapy, treatments with vitamin C and selenium are also helpful in muscle injuries. Therefore, considering the results of this study, it can be said that the level of injured muscle tissue improved significantly within 6 days.


Muscle injuries are common injuries in daily life. However, they pose a greater problem in athletes. Physical therapy and rehabilitation are used in both the acute and chronic phases of muscle injuries. In rats with gastrocnemius muscle contusion injury, treatment with therapeutic pulsed ultrasound (TPU) positively contributed to myoregeneration in the early stages of muscle damage. In a study in which a laceration injury was produced in the gastrocnemius muscle, TPU treatment was found to have a positive effect on the regeneration of the damaged muscle.

Van Yüzüncü Yıl University

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This page is a summary of: Investigation of the biochemical and histopathological effects of vitamin C, selenium, and therapeutic ultrasound on muscle damage in rats, Naunyn-Schmiedeberg s Archives of Pharmacology, June 2023, Springer Science + Business Media,
DOI: 10.1007/s00210-023-02547-w.
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