What is it about?
We suggest a battery of tests which can be used together to calculate a score which predicts the expansion and differentiation potential of mesenchymal stem cells.
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Why is it important?
The paper allows the user to implement a senescence score set which can be used as a performance prediction tool in laboratory research and possibly in stem cell therapy.
Perspectives
When we started the experiments for this paper there was a deficit on papers dealing with senescence in mesenchymal stem cells. In the mean time there are many such papers but the paper is still valuable for establishing a systematic approach in how to assess senescence and link it to cell performance.
Dr Jivko Stoyanov
Swiss Paraplegic Research
Read the Original
This page is a summary of: Anin vitroexpansion score for tissue-engineering applications with human bone marrow-derived mesenchymal stem cells, Journal of Tissue Engineering and Regenerative Medicine, April 2013, Wiley,
DOI: 10.1002/term.1734.
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