Black Tea improves dyspepsia associated with sildenafil

What is it about?

Sildenafil was approved in 1998 by the Food and Drug Administration for treatment of erectile dysfunction (impotence), and then in 2005 for treatment of pulmonary hypertension. Sildenafil-dyspeptic complaints could be explained by inhibited gut motility. It was found that black tea extract (BTE) and its thearubigins (TRs) improved the sildenafil-induced delay in gastric emptying (GE) and small intestinal transit (SIT) in mice. Thus, BTE could be recommended as a reliever therapy for SLD-induced gastrointestinal dysfunction.

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