Comparative top down proteomics of peripheral blood mononuclear cells from kidney transplant recipients with normal kidney biopsies or acute rejection

What is it about?

In this article, biological mass spectrometrists and transplant surgeons work together to track allograft outcomes using high throughput, intact proteome analysis.

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Why is it important?

This work represents a landmark foray of next-gen top-down proteomics technology as a discovery tool in translational and clinical spheres, namely transplant immunobiology.