What is it about?
Daidzein in soy bean is known to be converted to equol by intestinal microorganisms when we orally ingested daidzein. We have found daidzein has been found to be anti-diabetic. However, little is known whether or not equal is antidibetic or not. In this article, thus, antidiabetic action of equol and molecular mechanism, if any, was investigated.
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Why is it important?
People who can convert daidzein to equol are called equol-producers, while those cannot are called equol-nonproducers. Producers or non-producers are considered to depends on their food habit and culture. If equol is antidiabetic, it is useful for equol-nonproducers to prevent or suppress the onset of diabetes.
Perspectives
Equol is already used as a supplement. This paper described actions of equol on diabetes and its molecular mechansims at the molecular, cellular and whole body levels. Thus, the article is considered to supply useful and scientific evidence for equol against type 2 diabetes.
Dr Kazumi Yagasaki
Tokyo University of Agriculture & Technology
Read the Original
This page is a summary of: Antihyperglycemic effect of equol, a daidzein derivative, in cultured L6 myocytes andob/obmice, Molecular Nutrition & Food Research, September 2013, Wiley,
DOI: 10.1002/mnfr.201300272.
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