What is it about?
This paper describes the enhanced delivery of molecules to the brain by ADTC5 cyclic peptide derived from E-cadherin sequence.
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Why is it important?
This is important to deliver drug molecules to the brain. Here, ADTC5 cyclic peptide enhance the delivery of molecules to the brian in the mouse model.
Perspectives
This paper shows that it is possible to improve delivery of drugs to the brain through the intercellular junctions of the blood-brain barrier.
Professor Teruna J Siahaan
University of Kansas
Read the Original
This page is a summary of: Modulation of Intercellular Junctions by Cyclic-ADT Peptides as a Method to Reversibly Increase Blood–Brain Barrier Permeability, Journal of Pharmaceutical Sciences, March 2015, Elsevier,
DOI: 10.1002/jps.24309.
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