All Stories

  1. Selectively Targeting Leukemic MOLT-4 Cells by MTX-cIBR Conjugate: Mechanism of Action and Cellular Entry

    Article • Life, June 2026, MDPI AG

    Distinguished Professor Teruna J Siahaan

  2. Targeting Hyaluronic Acid Increases Brain Retention of Intraventricular Dosed Antibodies in Mice

    Article • Molecular Pharmaceutics, January 2026, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  3. Site- and Size-Controlled PEGylation Modulates Biointerfaces and Immunoregulatory Functions of Bifunctional Peptides in an Autoimmune Disease Model

    Article • ACS Applied Materials & Interfaces, January 2026, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  4. Route of Administration Determines the Immunosuppressive Mechanism of Bifunctional Peptide Inhibitors in a Mouse EAE Model

    Article • Molecular Pharmaceutics, December 2025, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  5. Design and Synthesis of MBP-Fc-Bifunctional Peptide Inhibitor to Improve In Vivo Half-Life and Efficacy

    Article • Molecular Pharmaceutics, November 2025, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  6. Overcoming Synthetic Challenges and Evaluating in Vivo Efficacy of the MOG-Fc-Bifunctional Peptide Inhibitor for EAE in Mice

    Article • Bioconjugate Chemistry, November 2025, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  7. Design, Structural Stability, Membrane Binding, and Antibacterial Activity of Novel Antimicrobial Peptides Derived from Wuchuanin-A1

    Article • Life, October 2025, MDPI AG

    Distinguished Professor Teruna J Siahaan

  8. Improving conformational stability and bacterial membrane interactions of antimicrobial peptides with amphipathic helical structure

    Article • Medicinal Chemistry Research, October 2025, Springer Science + Business Media

    Distinguished Professor Teruna J Siahaan

  9. Investigating the impact of charge and hydrophilicity on peptide-mucin interactions using a simple mucin model

    Article • AAPS Open, October 2025, Springer Science + Business Media

    Distinguished Professor Teruna J Siahaan

  10. Systematic Search for Blood–Brain Barrier Modulating Peptides Based on Exhaustive E-Cadherin Domain–Domain Docking

    Article • Journal of Chemical Information and Modeling, September 2025, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  11. Directing cell delivery to murine atherosclerotic aortic lesions via targeting inflamed circulatory interface using nanocarriers

    Article • Frontiers in Cardiovascular Medicine, June 2025, Frontiers

    Distinguished Professor Teruna J Siahaan

  12. Formulation development and feasibility of AAV5 as a lyophilized drug product

    Article • Journal of Pharmaceutical Sciences, February 2025, Elsevier

    Distinguished Professor Teruna J Siahaan

  13. Innovative CDR grafting and computational methods for PD-1 specific nanobody design

    Article • Frontiers in Bioinformatics, January 2025, Frontiers

    Distinguished Professor Teruna J Siahaan

  14. Peptide Design for Enhanced Anti-Melanogenesis: Optimizing Molecular Weight, Polarity, and Cyclization

    Article • Drug Design Development and Therapy, January 2025, Taylor & Francis

    Distinguished Professor Teruna J Siahaan

  15. Structure of a Cyclic Peptide as an Inhibitor of Mycobacterium tuberculosis Transcription: NMR and Molecular Dynamics Simulations

    Article • Pharmaceuticals, November 2024, MDPI AG

    Distinguished Professor Teruna J Siahaan

  16. Delivery of Neuroregenerative Proteins to the Brain for Treatments of Neurodegenerative Brain Diseases

    Article • Life, November 2024, MDPI AG

    Distinguished Professor Teruna J Siahaan

  17. Exploring How Antibody Format Drives Clearance from the Brain

    Article • Molecular Pharmaceutics, July 2024, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  18. Mechanism of the blood-brain barrier modulation by cadherin peptides

    Article • June 2024, Open Exploration Publishing

    Distinguished Professor Teruna J Siahaan

  19. Selective Uptake of Macromolecules to the Brain in Microfluidics and Animal Models Using the HAVN1 Peptide as a Blood-Brain Barrier Modulator

    Article • Molecular Pharmaceutics, February 2024, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  20. Enhancing Antibody Exposure in the Central Nervous System: Mechanisms of Uptake, Clearance, and Strategies for Improved Brain Delivery

    Article • Journal of Nanotheranostics, October 2023, MDPI AG

    Distinguished Professor Teruna J Siahaan

  21. M. tuberculosis Transcription Machinery: A Review on the Mycobacterial RNA Polymerase and Drug Discovery Efforts

    Article • Life, November 2022, MDPI AG

    Distinguished Professor Teruna J Siahaan

  22. Spermidine/Spermine N1-Acetyltransferase 1 (SAT1)—A Potential Gene Target for Selective Sensitization of Glioblastoma Cells Using an Ionizable Lipid Nanoparticle to Deliver siRNA

    Article • Cancers, October 2022, MDPI AG

    Distinguished Professor Teruna J Siahaan

  23. Structural Design and Synthesis of Novel Cyclic Peptide Inhibitors Targeting Mycobacterium tuberculosis Transcription

    Article • Life, August 2022, MDPI AG

    Distinguished Professor Teruna J Siahaan

  24. Immune Modulation by Antigenic Peptides and Antigenic Peptide Conjugates for Treatment of Multiple Sclerosis

    Article • Medical Research Archives, January 2022, Knowledge Enterprise Journals

    Distinguished Professor Teruna J Siahaan

  25. Enhancing Intestinal Absorption of a Model Macromolecule via the Paracellular Pathway using E-Cadherin Peptides

    Article • Journal of Pharmaceutical Sciences, May 2021, Elsevier

    Distinguished Professor Teruna J Siahaan

  26. Doxorubicin-loaded iron oxide nanoparticles for glioblastoma therapy: a combinational approach for enhanced delivery of nanoparticles

    Article • Scientific Reports, July 2020, Springer Science + Business Media

    Distinguished Professor Teruna J Siahaan

  27. Non-invasive Brain Delivery and Efficacy of BDNF in APP/PS1 Transgenic Mice

    Article • Medical Research Archives, January 2020, Knowledge Enterprise Journals

    Distinguished Professor Teruna J Siahaan

  28. Noninvasive Brain Delivery and Efficacy of BDNF to Stimulate Neuroregeneration and Suppression of Disease Relapse in EAE Mice

    Article • Molecular Pharmaceutics, December 2019, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  29. Improving In Vivo Brain Delivery of Monoclonal Antibody Using Novel Cyclic Peptides

    Article • Pharmaceutics, October 2019, MDPI AG

    Distinguished Professor Teruna J Siahaan

  30. In Vivo Brain Delivery and Brain Deposition of Proteins with Various Sizes

    Article • Molecular Pharmaceutics, October 2019, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  31. Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors

    Article • Pharmaceutics, September 2019, MDPI AG

    Distinguished Professor Teruna J Siahaan

  32. Orf239342 from the mushroom Agaricus bisporus is a mannose binding protein

    Article • Biochemical and Biophysical Research Communications, July 2019, Elsevier

    Distinguished Professor Teruna J Siahaan

  33. Methotrexate disposition, anti-folate activity and efficacy in the collagen-induced arthritis mouse model

    Article • European Journal of Pharmacology, June 2019, Elsevier

    Distinguished Professor Teruna J Siahaan

  34. Protein PEGylation for cancer therapy: bench to bedside

    Article • Journal of Cell Communication and Signaling, November 2018, Springer Science + Business Media

    Distinguished Professor Teruna J Siahaan

  35. Conjugates of Cell Adhesion Peptides

    Article • Current Topics in Medicinal Chemistry, February 2018, Bentham Science Publishers

    Distinguished Professor Teruna J Siahaan

  36. Enhancing In Vivo Brain Delivery of Peptide and Protein Molecules in Animal Models

    Article • Nanotheranostics, January 2017, Ivyspring International Publisher

    Distinguished Professor Teruna J Siahaan

  37. Drug Delivery

    Article • May 2016, Wiley

    Distinguished Professor Teruna J Siahaan

  38. Physiological, Biochemical, and Chemical Barriers to Oral Drug Delivery

    Article • March 2016, Wiley

    Distinguished Professor Teruna J Siahaan

  39. Meet Our Regional Editor:

    Article • Medicinal Chemistry, January 2016, Bentham Science Publishers

    Distinguished Professor Teruna J Siahaan

  40. Prodrug strategies for brain delivery

    Article • June 2015, Future Science

    Distinguished Professor Teruna J Siahaan

  41. Modulation of Intercellular Junctions by Cyclic-ADT Peptides as a Method to Reversibly Increase Blood–Brain Barrier Permeability

    Article • Journal of Pharmaceutical Sciences, March 2015, Elsevier

    Distinguished Professor Teruna J Siahaan

  42. Routes of Administration and Dose Optimization of Soluble Antigen Arrays in Mice with Experimental Autoimmune Encephalomyelitis

    Article • Journal of Pharmaceutical Sciences, February 2015, Elsevier

    Distinguished Professor Teruna J Siahaan

  43. Co-Delivery of Autoantigen and B7 Pathway Modulators Suppresses Experimental Autoimmune Encephalomyelitis

    Article • The AAPS Journal, October 2014, American Association of Pharmaceutical Scientists (AAPS)

    Distinguished Professor Teruna J Siahaan

  44. Pathways and progress in improving drug delivery through the intestinal mucosa and blood–brain barriers

    Article • Therapeutic Delivery, October 2014, Future Science

    Distinguished Professor Teruna J Siahaan

  45. Structure, Size, and Solubility of Antigen Arrays Determines Efficacy in Experimental Autoimmune Encephalomyelitis

    Article • The AAPS Journal, September 2014, American Association of Pharmaceutical Scientists (AAPS)

    Distinguished Professor Teruna J Siahaan

  46. Modulation of Blood–Brain Barrier Permeability in Mice Using Synthetic E-Cadherin Peptide

    Article • Molecular Pharmaceutics, March 2014, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  47. 1H, 13C and 15N backbone assignment of the EC-1 domain of human E-cadherin

    Article • Biomolecular NMR Assignments, February 2014, Springer Science + Business Media

    Distinguished Professor Teruna J Siahaan

  48. Hyaluronic Acid Graft Polymers Displaying Peptide Antigen Modulate Dendritic Cell Response in Vitro

    Article • Molecular Pharmaceutics, January 2014, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  49. Codelivery of antigen and an immune cell adhesion inhibitor is necessary for efficacy of soluble antigen arrays in experimental autoimmune encephalomyelitis

    Article • Molecular Therapy — Methods & Clinical Development, January 2014, Elsevier

    Distinguished Professor Teruna J Siahaan

  50. Suppression of MOG- and PLP-induced experimental autoimmune encephalomyelitis using a novel multivalent bifunctional peptide inhibitor

    Article • Journal of Neuroimmunology, October 2013, Elsevier

    Distinguished Professor Teruna J Siahaan

  51. Single-step grafting of aminooxy-peptides to hyaluronan: A simple approach to multifunctional therapeutics for experimental autoimmune encephalomyelitis

    Article • Journal of Controlled Release, June 2013, Elsevier

    Distinguished Professor Teruna J Siahaan

  52. Biodegradable Nanoparticles Surface Modification Techniques With cIBR Peptide Targeting to LFA-1 Expressing Leukemic Cells

    Article • Journal of Nanotechnology in Engineering and Medicine, March 2013, ASME International

    Distinguished Professor Teruna J Siahaan

  53. Controlling immune response and demyelination using highly potent bifunctional peptide inhibitors in the suppression of experimental autoimmune encephalomyelitis

    Article • Clinical & Experimental Immunology, March 2013, Wiley

    Distinguished Professor Teruna J Siahaan

  54. Vaccinelike and Prophylactic Treatments of EAE with Novel I-Domain Antigen Conjugates (IDAC): Targeting Multiple Antigenic Peptides to APC

    Article • Molecular Pharmaceutics, January 2013, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  55. Peptide Delivery

    Article • January 2013, Elsevier

    Distinguished Professor Teruna J Siahaan

  56. Chemical Pathways of Peptide and Protein Degradation

    Article • November 2012, Taylor & Francis

    Distinguished Professor Teruna J Siahaan

  57. Methotrexate (MTX)–cIBR Conjugate for Targeting MTX to Leukocytes: Conjugate Stability and In Vivo Efficacy in Suppressing Rheumatoid Arthritis

    Article • Journal of Pharmaceutical Sciences, September 2012, Elsevier

    Distinguished Professor Teruna J Siahaan

  58. Immune modulating peptides for the treatment and suppression of multiple sclerosis

    Article • Clinical Immunology, August 2012, Elsevier

    Distinguished Professor Teruna J Siahaan

  59. Improving the stability of the EC1 domain of E-cadherin by thiol alkylation of the cysteine residue

    Article • International Journal of Pharmaceutics, July 2012, Elsevier

    Distinguished Professor Teruna J Siahaan

  60. Vaccine-like Controlled-Release Delivery of an Immunomodulating Peptide To Treat Experimental Autoimmune Encephalomyelitis

    Article • Molecular Pharmaceutics, April 2012, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  61. I-Domain-Antigen Conjugate (IDAC) for Delivering Antigenic Peptides to APC: Synthesis, Characterization, and in Vivo EAE Suppression

    Article • Bioconjugate Chemistry, March 2012, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  62. Suppression of EAE and prevention of blood–brain barrier breakdown after vaccination with novel bifunctional peptide inhibitor

    Article • Neuropharmacology, March 2012, Elsevier

    Distinguished Professor Teruna J Siahaan

  63. Peptides and Proteins for Treatment and Suppression of Type 1 Diabetes

    Article • November 2011, IntechOpen

    Distinguished Professor Teruna J Siahaan

  64. Rapid Identification of Fluorochrome Modification Sites in Proteins by LC ESI-Q-TOF Mass Spectrometry

    Article • Bioconjugate Chemistry, July 2011, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  65. Autoimmune therapies targeting costimulation and emerging trends in multivalent therapeutics

    Article • Therapeutic Delivery, July 2011, Future Science

    Distinguished Professor Teruna J Siahaan

  66. Calcium Condensed LABL-TAT Complexes Effectively Target Gene Delivery to ICAM-1 Expressing Cells

    Article • Molecular Pharmaceutics, June 2011, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  67. Antigen-specific blocking of CD4-Specific immunological synapse formation using BPI and current therapies for autoimmune diseases

    Article • Medicinal Research Reviews, March 2011, Wiley

    Distinguished Professor Teruna J Siahaan

  68. Nanoparticles Targeting Dendritic Cell Surface Molecules Effectively Block T Cell Conjugation and Shift Response

    Article • ACS Nano, March 2011, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  69. Controlling Ligand Surface Density Optimizes Nanoparticle Binding to ICAM-1

    Article • Journal of Pharmaceutical Sciences, March 2011, Elsevier

    Distinguished Professor Teruna J Siahaan

  70. Enhancement of Drug Absorption through the Blood−Brain Barrier and Inhibition of Intercellular Tight Junction Resealing by E-Cadherin Peptides

    Article • Molecular Pharmaceutics, February 2011, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  71. MODULASI JUNCTION ANTAR SEL MENGGUNAKAN PEPTIDA KADHERIN UPAYA MENINGKATKAN PENGHANTARAN OBAT

    Article • MAKARA of Science Series, October 2010, Universitas Indonesia, Directorate of Research and Public Service

    Distinguished Professor Teruna J Siahaan

  72. Peptide-mediated targeted drug delivery

    Article • Medicinal Research Reviews, September 2010, Wiley

    Distinguished Professor Teruna J Siahaan

  73. ChemInform Abstract: Oxazolophanes as Masked Cyclopeptide Alkaloid Equivalents: Cyclic Peptide Chemistry without Peptide Couplings.

    Article • ChemInform, August 2010, Wiley

    Distinguished Professor Teruna J Siahaan

  74. ChemInform Abstract: Delocalized Carbanions in Synthesis

    Article • ChemInform, August 2010, Wiley

    Distinguished Professor Teruna J Siahaan

  75. LFA-1 on Leukemic Cells as a Target for Therapy or Drug Delivery

    Article • Current Pharmaceutical Design, July 2010, Bentham Science Publishers

    Distinguished Professor Teruna J Siahaan

  76. A Peptide from the Beta-strand Region of CD2 Protein that Inhibits Cell Adhesion and Suppresses Arthritis in a Mouse Model

    Article • Chemical Biology & Drug Design, June 2010, Wiley

    Distinguished Professor Teruna J Siahaan

  77. ChemInform Abstract: Synthesis of an Esterase-Sensitive Cyclic Prodrug of a Model Hexapeptide Having Enhanced Membrane Permeability and Enzymic Stability Using a 3-(2′-Hydroxy-4′,6′-dimethylphenyl)-3,3-Dimethylpropionic Acid Promoiety

    Article • ChemInform, June 2010, Wiley

    Distinguished Professor Teruna J Siahaan

  78. ChemInform Abstract: Synthesis of an Esterase-Sensitive Cyclic Prodrug of a Model Hexapeptide Having Enhanced Membrane Permeability and Enzymatic Stability Using an Acyloxyalkoxy Promoiety

    Article • ChemInform, June 2010, Wiley

    Distinguished Professor Teruna J Siahaan

  79. ChemInform Abstract: Steric Hindrance is a Key Factor in the Coupling Reaction of (Acyloxy) Alkyl-α-halides with Phenols to Make a New Promoiety for Prodrugs.

    Article • ChemInform, May 2010, Wiley

    Distinguished Professor Teruna J Siahaan

  80. ChemInform Abstract: Inhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a Therapeutic Approach to Inflammation and Autoimmune Diseases

    Article • ChemInform, May 2010, Wiley

    Distinguished Professor Teruna J Siahaan

  81. cIBR Effectively Targets Nanoparticles to LFA-1 on Acute Lymphoblastic T Cells

    Article • Molecular Pharmaceutics, February 2010, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  82. Immune response to controlled release of immunomodulating peptides in a murine experimental autoimmune encephalomyelitis (EAE) model

    Article • Journal of Controlled Release, January 2010, Elsevier

    Distinguished Professor Teruna J Siahaan

  83. Antigen-Specific Suppression of Experimental Autoimmune Encephalomyelitis by a Novel Bifunctional Peptide Inhibitor: Structure Optimization and Pharmacokinetics

    Article • Journal of Pharmacology and Experimental Therapeutics, December 2009, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Distinguished Professor Teruna J Siahaan

  84. The Role of Thiols and Disulfides on Protein Stability

    Article • Current Protein and Peptide Science, December 2009, Bentham Science Publishers

    Distinguished Professor Teruna J Siahaan

  85. The Role of Covalent Dimerization on the Physical and Chemical Stability of the EC1 Domain of Human E-Cadherin

    Article • Journal of Pharmaceutical Sciences, October 2009, Elsevier

    Distinguished Professor Teruna J Siahaan

  86. Solution structure of a novel T-cell adhesion inhibitor derived from the fragment of ICAM-1 receptor: Cyclo(1,8)-Cys-Pro-Arg-Gly-Gly-Ser-Val-Cys

    Article • Biopolymers, August 2009, Wiley

    Distinguished Professor Teruna J Siahaan

  87. Adhesion of pancreatic beta cells to biopolymer films

    Article • Biopolymers, August 2009, Wiley

    Distinguished Professor Teruna J Siahaan

  88. Characterization of Multiple Stable Conformers of the EC5 Domain of E-cadherin and the Interaction of EC5 with E-cadherin Peptides

    Article • Chemical Biology & Drug Design, June 2009, Wiley

    Distinguished Professor Teruna J Siahaan

  89. ICAM-1 targeting of doxorubicin-loaded PLGA nanoparticles to lung epithelial cells

    Article • European Journal of Pharmaceutical Sciences, May 2009, Elsevier

    Distinguished Professor Teruna J Siahaan

  90. Effect of Modification of the Physicochemical Properties of ICAM-1-Derived Peptides on Internalization and Intracellular Distribution in the Human Leukemic Cell Line HL-60

    Article • Molecular Pharmaceutics, April 2009, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  91. The aqueous conformation of cyclo(1,6)Ac-Cys-Arg-Gly-Asp-Phe-Pen-NH2

    Article • International journal of peptide & protein research, January 2009, Wiley

    Distinguished Professor Teruna J Siahaan

  92. Conformational analysis of cyclo(2,9)-Ac-QCRSVEGSCG-OH from the C-terminal loop of human growth hormone

    Article • Journal of Peptide Research, January 2009, Wiley

    Distinguished Professor Teruna J Siahaan

  93. Inhibition of homotypic adhesion of T-cells: secondary structure of an ICAM-1-derived cyclic peptide

    Article • Journal of Peptide Research, January 2009, Wiley

    Distinguished Professor Teruna J Siahaan

  94. Evaluation of the physical stability of the EC5 domain of E-cadherin: Effects of pH, temperature, ionic strength, and disulfide bonds

    Article • Journal of Pharmaceutical Sciences, January 2009, Elsevier

    Distinguished Professor Teruna J Siahaan

  95. Prophylactic and therapeutic suppression of experimental autoimmune encephalomyelitis by a novel bifunctional peptide inhibitor

    Article • Clinical Immunology, October 2008, Elsevier

    Distinguished Professor Teruna J Siahaan

  96. Structural Modifications of ICAM-1 Cyclic Peptides to Improve the Activity to Inhibit Heterotypic Adhesion of T cells

    Article • Chemical Biology & Drug Design, July 2008, Wiley

    Distinguished Professor Teruna J Siahaan

  97. PLGA Nanoparticle−Peptide Conjugate Effectively Targets Intercellular Cell-Adhesion Molecule-1

    Article • Bioconjugate Chemistry, January 2008, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  98. Mechanism of Internalization of an ICAM-1-Derived Peptide by Human Leukemic Cell Line HL-60: Influence of Physicochemical Properties on Targeted Drug Delivery

    Article • Molecular Pharmaceutics, October 2007, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  99. ICAM-1 Peptide Inhibitors of T-cell Adhesion bind to the allosteric site of LFA-1. An NMR Characterization

    Article • Chemical Biology & Drug Design, October 2007, Wiley

    Distinguished Professor Teruna J Siahaan

  100. ICAM-1 Peptide Inhibitors of T-cell Adhesion bind to the allosteric site of LFA-1. An NMR Characterization

    Article • Chemical Biology & Drug Design, September 2007, Wiley

    Distinguished Professor Teruna J Siahaan

  101. Sequence Recognition of ?-LFA-1-derived Peptides by ICAM-1 Cell Receptors: Inhibitors of T-cell Adhesion

    Article • Chemical Biology & Drug Design, September 2007, Wiley

    Distinguished Professor Teruna J Siahaan

  102. Suppression of Type 1 Diabetes in NOD Mice by Bifunctional Peptide Inhibitor: Modulation of the Immunological Synapse Formation

    Article • Chemical Biology & Drug Design, September 2007, Wiley

    Distinguished Professor Teruna J Siahaan

  103. Antigen-Specific Suppression of Experimental Autoimmune Encephalomyelitis by a Novel Bifunctional Peptide Inhibitor

    Article • Journal of Pharmacology and Experimental Therapeutics, May 2007, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Distinguished Professor Teruna J Siahaan

  104. Cell Adhesion Molecules for Targeted Drug Delivery

    Article • Journal of Pharmaceutical Sciences, January 2007, Elsevier

    Distinguished Professor Teruna J Siahaan

  105. Synthesis and chemical stability of a disulfide bond in a model cyclic pentapeptide: Cyclo(1,4)‐Cys‐Gly‐Phe‐Cys‐Gly‐OH

    Article • Journal of Pharmaceutical Sciences, October 2006, Elsevier

    Distinguished Professor Teruna J Siahaan

  106. Cell Adhesion Molecules for Targeted Drug Delivery

    Article • Journal of Pharmaceutical Sciences, September 2006, Elsevier

    Distinguished Professor Teruna J Siahaan

  107. Structure and Function of the Intercellular Junctions: Barrier of Paracellular Drug Delivery

    Article • Current Pharmaceutical Design, August 2006, Bentham Science Publishers

    Distinguished Professor Teruna J Siahaan

  108. Characterization of Binding Properties of ICAM-1 Peptides to LFA-1: Inhibitors of T-cell Adhesion

    Article • Chemical Biology & Drug Design, July 2006, Wiley

    Distinguished Professor Teruna J Siahaan

  109. Effects of Amino Acid Chirality and the Chemical Linker on the Cell Permeation Characteristics of Cyclic Prodrugs of Opioid Peptides

    Article • Journal of Medicinal Chemistry, February 2006, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  110. Deamidation of model β-turn cyclic peptides in the solid state

    Article • Journal of Pharmaceutical Sciences, December 2005, Elsevier

    Distinguished Professor Teruna J Siahaan, Dr Gerald H Lushington

  111. Modulation of Cell Adhesion Molecules in Various Epithelial Cell Lines after Treatment with PP2 †

    Article • Molecular Pharmaceutics, June 2005, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  112. Physiological, Biochemical, and Chemical Barriers to Oral Drug Delivery

    Article • May 2005, Wiley

    Distinguished Professor Teruna J Siahaan

  113. Drug Delivery

    Article • March 2005, Wiley

    Distinguished Professor Teruna J Siahaan

  114. Effects of An E-cadherin-Derived Peptide on the Gene Expression of Caco-2 Cells

    Article • Pharmaceutical Research, November 2004, Springer Science + Business Media

    Distinguished Professor Teruna J Siahaan

  115. Design, structure and biological activity of β-turn peptides of CD2 protein for inhibition of T-cell adhesion

    Article • FEBS Journal, June 2004, Wiley

    Distinguished Professor Teruna J Siahaan

  116. Inhibition of ICAM-1/LFA-1-mediated heterotypic T-cell adhesion to epithelial cells: design of ICAM-1 cyclic peptides

    Article • Bioorganic & Medicinal Chemistry Letters, March 2004, Elsevier

    Distinguished Professor Teruna J Siahaan

  117. Reductive Alkylation of Lipase: Experimental and Molecular Modeling Approaches

    Article • Applied Biochemistry and Biotechnology, January 2004, Springer Science + Business Media

    Distinguished Professor Teruna J Siahaan

  118. Expression, purification, and structural study of the EC4 domain of E-cadherin

    Article • Protein Expression and Purification, January 2004, Elsevier

    Distinguished Professor Teruna J Siahaan

  119. Solution structure of a peptide derived from the β subunit of LFA-1

    Article • Peptides, June 2003, Elsevier

    Distinguished Professor Teruna J Siahaan

  120. Syntheses of cyclic prodrugs of RGD peptidomimetics with various macrocyclic ring sizes: evaluation of physicochemical, transport and antithrombic properties

    Article • Journal of Peptide Research, May 2003, Wiley

    Distinguished Professor Teruna J Siahaan

  121. Synthesis and comparison of physicochemical, transport, and antithrombic properties of a cyclic prodrug and the parent RGD peptidomimetic

    Article • Tetrahedron, April 2003, Elsevier

    Distinguished Professor Teruna J Siahaan

  122. A Peptide Derived from LFA-1 Protein that Modulates T-cell Adhesion Binds to Soluble ICAM-1 Protein

    Article • Journal of Biomolecular Structure and Dynamics, April 2003, Taylor & Francis

    Distinguished Professor Teruna J Siahaan

  123. Targeting ICAM-1/LFA-1 interaction for controlling autoimmune diseases: designing peptide and small molecule inhibitors

    Article • Peptides, March 2003, Elsevier

    Distinguished Professor Teruna J Siahaan

  124. Synthesis and stability study of a modified phenylpropionic acid linker-based esterase-sensitive prodrug

    Article • Bioorganic & Medicinal Chemistry Letters, December 2002, Elsevier

    Distinguished Professor Teruna J Siahaan

  125. Localized production of human E-cadherin-derived first repeat in Escherichia coli

    Article • Protein Expression and Purification, December 2002, Elsevier

    Distinguished Professor Teruna J Siahaan

  126. Synthesis of a novel cyclic prodrug of RGD peptidomimetic to improve its cell membrane permeation

    Article • Bioorganic Chemistry, August 2002, Elsevier

    Distinguished Professor Teruna J Siahaan

  127. Structural and ICAM-1-Docking Properties of a Cyclic Peptide from the I-domain of LFA-1: An inhibitor of ICAM-1/LFA-1-mediated T-cell adhesion

    Article • Journal of Biomolecular Structure and Dynamics, April 2002, Taylor & Francis

    Distinguished Professor Teruna J Siahaan

  128. Molecular Dynamics Simulations of Conformational Behavior of Linear RGD Peptidomimetics and Cyclic Prodrugs in Aqueous and Octane Solutions

    Article • Journal of Biomolecular Structure and Dynamics, April 2002, Taylor & Francis

    Distinguished Professor Teruna J Siahaan

  129. Synthesis and conformational analysis of a coumarinic acid-based cyclic prodrug of an opioid peptide with modified sensitivity to esterase-catalyzed bioconversion

    Article • Journal of Peptide Research, March 2002, Wiley

    Distinguished Professor Teruna J Siahaan

  130. Modeling alternative binding registers of a minimal immunogenic peptide on two class II major histocompatibility complex (MHC II) molecules predicts polarized T-cell receptor (TCR) contact positions

    Article • Journal of Peptide Research, March 2002, Wiley

    Distinguished Professor Teruna J Siahaan

  131. Inhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a therapeutic approach to inflammation and autoimmune diseases

    Article • Medicinal Research Reviews, February 2002, Wiley

    Distinguished Professor Teruna J Siahaan

  132. Synthesis of Cyclic Prodrugs of Aggrastat and Its Analogue with a Modified Phenylpropionic Acid Linker

    Article • Organic Letters, February 2002, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  133. Steric hindrance is a key factor in the coupling reaction of (acyloxy) alkyl-α-halides with phenols to make a new promoiety for prodrugs

    Article • Tetrahedron Letters, January 2002, Elsevier

    Distinguished Professor Teruna J Siahaan

  134. Synergistic inhibitory activity of α- and β-LFA-1 peptides on LFA-1/ICAM-1 interaction

    Article • Peptides, December 2001, Elsevier

    Distinguished Professor Teruna J Siahaan

  135. Rapid Determination of Substrate Specificity of Clostridium histolyticum  -Collagenase Using an Immobilized Peptide Library

    Article • Journal of Biological Chemistry, November 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Distinguished Professor Teruna J Siahaan

  136. Regulation of Cadherin-Cadherin Interaction: Secondary Structure of the HAV and ADT Peptides Derived from Human E-Cadherin Sequence

    Article • January 2001, Springer Science + Business Media

    Distinguished Professor Teruna J Siahaan

  137. Utilization of ICAM-1 Peptide Conjugates for Drug Targeting to T-Cells

    Article • January 2001, Springer Science + Business Media

    Distinguished Professor Teruna J Siahaan

  138. Conjugation with L-Glutamate forin vivoBrain Drug Delivery

    Article • Journal of Drug Targeting, January 2001, Taylor & Francis

    Distinguished Professor Teruna J Siahaan

  139. Linear and cyclic LFA-1 and ICAM-1 peptides inhibit T cell adhesion and function

    Article • Peptides, August 2000, Elsevier

    Distinguished Professor Teruna J Siahaan

  140. Effect of Conformation on the Rate of Deamidation of Vancomycin in Aqueous Solutions

    Article • Journal of Pharmaceutical Sciences, June 2000, Elsevier

    Distinguished Professor Teruna J Siahaan

  141. Enhancement of Transport of D-Melphalan Analogue by Conjugation with L-Glutamate across Bovine Brain Microvessel Endothelial Cell Monolayers

    Article • Journal of Drug Targeting, January 2000, Taylor & Francis

    Distinguished Professor Teruna J Siahaan

  142. Comparison of the Solution Conformations of a Cell-Adhesive Peptide LBE and its Reverse Sequence EBL

    Article • Journal of Biomolecular Structure and Dynamics, December 1999, Taylor & Francis

    Distinguished Professor Teruna J Siahaan

  143. PEPTIDES DERIVED FROM ICAM-1 AND LFA-1 MODULATE T CELL ADHESION AND IMMUNE FUNCTION IN A MIXED LYMPHOCYTE CULTURE1

    Article • Transplantation, September 1999, Wolters Kluwer Health

    Distinguished Professor Teruna J Siahaan

  144. Effect of conformation on the conversion of cyclo-(1,7)-Gly-Arg-Gly-Asp-Ser-Pro-Asp-Gly-OH to its cyclic imide degradation product

    Article • Journal of Peptide Research, July 1999, Wiley

    Distinguished Professor Teruna J Siahaan

  145. Solution stability of linear vs. cyclic RGD peptides

    Article • Journal of Peptide Research, May 1999, Wiley

    Distinguished Professor Teruna J Siahaan

  146. The effect of conformation on the solution stability of linear vs. cyclic RGD peptides

    Article • Journal of Peptide Research, May 1999, Wiley

    Distinguished Professor Teruna J Siahaan

  147. Binding and internalization of an ICAM‐1 peptide by the surface receptors of T cells

    Article • Journal of Peptide Research, April 1999, Wiley

    Distinguished Professor Teruna J Siahaan

  148. The effect of conformation on the membrane permeation of coumarinic acid‐ and phenylpropionic acid‐based cyclic prodrugs of opioid peptides

    Article • Journal of Peptide Research, April 1999, Wiley

    Distinguished Professor Teruna J Siahaan

  149. The effect of conformation of the acyloxyalkoxy‐based cyclic prodrugs of opioid peptides on their membrane permeability

    Article • Journal of Peptide Research, April 1999, Wiley

    Distinguished Professor Teruna J Siahaan

  150. Structural recognition of an ICAM‐1 peptide by its receptor on the surface of T cells: conformational studies of cyclo (1, 12)‐Pen‐Pro‐Arg‐Gly‐Gly‐Ser‐Val‐Leu‐Val‐Thr‐Gly‐Cys‐OH

    Article • Journal of Peptide Research, April 1999, Wiley

    Distinguished Professor Teruna J Siahaan

  151. Synthesis and evaluation of the physicochemical properties of esterase‐sensitive cyclic prodrugs of opioid peptides using coumarinic acid and phenylpropionic acid linkers

    Article • Journal of Peptide Research, April 1999, Wiley

    Distinguished Professor Teruna J Siahaan

  152. Synthesis and evaluation of the physicochemical properties of esterase‐sensitive cyclic prodrugs of opioid peptides using an (acyloxy)alkoxy linker

    Article • Journal of Peptide Research, April 1999, Wiley

    Distinguished Professor Teruna J Siahaan

  153. A Ca2+binding cyclic peptide derived from the ?-subunit of LFA-1: inhibitor of ICAM-1 /LFA-1-mediated T-cell adhesion

    Article • Journal of Peptide Research, January 1999, Wiley

    Distinguished Professor Teruna J Siahaan

  154. Molecular Structure of the Apical Junction Complex and Its Contribution to the Paracellular Barrier

    Article • Journal of Pharmaceutical Sciences, September 1997, Elsevier

    Distinguished Professor Teruna J Siahaan

  155. Separation and Analysis of Peptides and Proteins

    Article • Analytical Chemistry, June 1997, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  156. Modulation of Melphalan Resistance in Glioma Cells with a Peripheral Benzodiazepine Receptor Ligand−Melphalan Conjugate

    Article • Journal of Medicinal Chemistry, May 1997, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  157. Prodrug strategies to enhance the intestinal absorption of peptides

    Article • Drug Discovery Today, April 1997, Elsevier

    Distinguished Professor Teruna J Siahaan

  158. Synthesis of a Novel Esterase-Sensitive Cyclic Prodrug of a Hexapeptide Using an (Acyloxy)alkoxy Promoiety

    Article • The Journal of Organic Chemistry, March 1997, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  159. Synthesis of a Novel Esterase-Sensitive Cyclic Prodrug System for Peptides That Utilizes a “Trimethyl Lock”-Facilitated Lactonization Reaction

    Article • The Journal of Organic Chemistry, March 1997, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  160. Modulation of the Cellular Junction Protein E-Cadherin in Bovine Brain Microvessel Endothelial Cells by Cadherin Peptides

    Article • Drug Delivery, January 1997, Taylor & Francis

    Distinguished Professor Teruna J Siahaan

  161. Modulation of cellular adhesion in bovine brain microvessel endothelial cells by a decapeptide

    Article • Brain Research, January 1997, Elsevier

    Distinguished Professor Teruna J Siahaan

  162. Derivatives of Melphalan Designed to Enhance Drug Accumulation in Cancer Cells

    Article • Journal of Drug Targeting, January 1997, Taylor & Francis

    Distinguished Professor Teruna J Siahaan

  163. Novel esterase-sensitive cyclic prodrugs of a model hexapeptide having enhanced membrane permeability and enzymatic stability

    Article • January 1997, Elsevier

    Distinguished Professor Teruna J Siahaan

  164. Solution Structure of a Cyclic RGD Peptide That Inhibits Platelet Aggregation

    Article • Journal of Biomolecular Structure and Dynamics, August 1996, Taylor & Francis

    Distinguished Professor Teruna J Siahaan

  165. Structural requirements for intestinal absorption of peptide drugs

    Article • Journal of Controlled Release, August 1996, Elsevier

    Distinguished Professor Teruna J Siahaan

  166. Secondary Structure of the HAV Peptide Which Regulates Cadherin-Cadherin Interaction

    Article • Journal of Biomolecular Structure and Dynamics, December 1995, Taylor & Francis

    Distinguished Professor Teruna J Siahaan

  167. Separation and Analysis of Peptides and Proteins

    Article • Analytical Chemistry, June 1995, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  168. E-Cadherin Peptide Sequence Recognition by Anti-E-Cadherin Antibody

    Article • Biochemical and Biophysical Research Communications, June 1995, Elsevier

    Distinguished Professor Teruna J Siahaan

  169. Conformational study of cyclo[Gln-Trp-Phe-Gly-Leu-Met] as NK-2 antagonist by NMR and molecular dynamics

    Article • Journal of Pharmaceutical and Biomedical Analysis, January 1994, Elsevier

    Distinguished Professor Teruna J Siahaan

  170. Immobilized peptide arrays: A new technology for the characterization of protease function

    Article • January 1994, Springer Science + Business Media

    Distinguished Professor Teruna J Siahaan

  171. Conformational study of cyclo(1,5)-Ac-Pen-Arg-Gly-Asp-Cys-NH2 in water by NMR and molecular dynamics

    Article • Biochemical and Biophysical Research Communications, September 1992, Elsevier

    Distinguished Professor Teruna J Siahaan

  172. Delocalized Carbanions in Synthesis

    Article • Synlett, January 1991, Thieme Publishing Group

    Distinguished Professor Teruna J Siahaan

  173. Oxazolophanes as masked cyclopeptide alkaloid equivalents: cyclic peptide chemistry without peptide couplings

    Article • Journal of the American Chemical Society, September 1990, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  174. A new rearrangement of alkoxybenzyl anions

    Article • The Journal of Organic Chemistry, February 1990, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  175. The role of boron trifluoride etherate in reactions of lower order (Gilman) organocuprates

    Article • Journal of the American Chemical Society, February 1989, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  176. Modeling of the homoeo domain suggests similar structure to repressors

    Article • Biochemical and Biophysical Research Communications, November 1988, Elsevier

    Distinguished Professor Teruna J Siahaan

  177. Effects of boron trifluoride etherate on higher order organocuprate reactions: substrate activation or cuprate modification?

    Article • Journal of the American Chemical Society, July 1988, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  178. Sesquiterpenoid glycosides and an acetogenin glucoside from Lessingia glandulifera

    Article • Phytochemistry, January 1988, Elsevier

    Distinguished Professor Teruna J Siahaan

  179. Kolavane diterpenoids of Vanclevea stylosa

    Article • Phytochemistry, January 1988, Elsevier

    Distinguished Professor Teruna J Siahaan

  180. Grindelane diterpenoids from Isocoma tenuisecta

    Article • Phytochemistry, January 1988, Elsevier

    Distinguished Professor Teruna J Siahaan

  181. Unexpected affects of Me3Si-X on reactions of higher order cyanocuprates

    Article • Tetrahedron Letters, January 1988, Elsevier

    Distinguished Professor Teruna J Siahaan

  182. Preparation and reactions of trianions from the dimethylphenols

    Article • The Journal of Organic Chemistry, October 1987, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  183. Five grindelane diterpenoids from Grindelia acutifolia

    Article • Phytochemistry, January 1987, Elsevier

    Distinguished Professor Teruna J Siahaan

  184. Havardic acids A-F and havardiol, labdane diterpenoids from Grindelia havardii

    Article • Phytochemistry, January 1987, Elsevier

    Distinguished Professor Teruna J Siahaan

  185. A new diterpenoid from Ericameria laricifolia

    Article • Phytochemistry, January 1987, Elsevier

    Distinguished Professor Teruna J Siahaan

  186. A New Heterocyclic System from Salol and Phenylacetic Acid

    Article • Heterocycles, January 1987, Japan Institute of Heterocyclic Chemistry

    Distinguished Professor Teruna J Siahaan

  187. Preparation and reactions of dianions from cresols

    Article • The Journal of Organic Chemistry, May 1986, American Chemical Society (ACS)

    Distinguished Professor Teruna J Siahaan

  188. Labdane diterpenoids from Grindelia discoidea (asteraceae)

    Article • Phytochemistry, May 1986, Elsevier

    Distinguished Professor Teruna J Siahaan

  189. 9,10-Anthracenedicarbaldehyde bis[(4,5-dihydro-1H-imidazol-2-yl)hydrazone] acetic acid hydrochloric acid trihydrate salt (bisantrene)

    Article • Acta Crystallographica Section C Crystal Structure Communications, February 1986, International Union of Crystallography

    Distinguished Professor Teruna J Siahaan

  190. Cardenolides and a lignan from asclepias subulata

    Article • Phytochemistry, January 1986, Elsevier

    Distinguished Professor Teruna J Siahaan

  191. Diterpenoids and flavonoids from Grindelia discoidea

    Article • Phytochemistry, January 1986, Elsevier

    Distinguished Professor Teruna J Siahaan

  192. Utilization of cell-adhesion peptides to improve drug delivery

    Article • Springer Science + Business Media

    Distinguished Professor Teruna J Siahaan

  193. Cells activation modulates binding of an LFA-1 peptide to the T-cell adhesion receptors

    Article • Springer Science + Business Media

    Distinguished Professor Teruna J Siahaan

  194. Synthesis of an Esterase-Sensitive Cyclic Prodrug of a Model Hexapeptide Having Enhanced Membrane Permeability and Enzymatic Stability Using an Acyloxyalkoxy Promoiety

    Article • Springer Science + Business Media

    Distinguished Professor Teruna J Siahaan

  195. Synthesis of an Esterase-Sensitive Cyclic Prodrug of a Model Hexapeptide Having Enhanced Membrane Permeability and Enzymatic Stability Using a 3-(2'-Hydroxy-4',6'-Dimethylphenyl)-3,3-Dimethyl Propionic Acid Promoiety

    Article • Springer Science + Business Media

    Distinguished Professor Teruna J Siahaan

  196. Inhibition of E-cadherin-mediated cell-cell adhesion by cadherin peptides

    Article • Springer Science + Business Media

    Distinguished Professor Teruna J Siahaan