What is it about?
Discovery of novel activity of cleaving unsulfated polysaccharide from a point mutation.
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Why is it important?
Expanding the catalytic activity across PL family.
Perspectives
Change of the cleavage mode from beta-1,4 linkage to alpha-1,4 linkage of the sugar units.
Prof. Yijun Chen
China Pharmaceutical University
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This page is a summary of: Expanding the Catalytic Promiscuity of Heparinase III from Pedobacter heparinus, Chemistry - A European Journal, January 2017, Wiley,
DOI: 10.1002/chem.201605929.
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