What is it about?
Weak Bases‐Mediated Modified Favorskii Reaction‐Type Direct Alkynylation/(E)‐Alkenylation
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Why is it important?
With the rapid operational simplicity, functional group compatibility, and substrate selectivity; the present protocol demonstrates a fast method for the facile synthesis of bioactive scaffolds in good to excellent yields.
Perspectives
The gram‐scale synthesis and its practical applications to the synthesis of bioactive heterocyclic scaffolds further highlight the practicality of this methodology.
Dr. MOHIT K TIWARI
Malaviya National Institute of Technology
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This page is a summary of: Weak Bases‐Mediated Modified Favorskii Reaction‐Type Direct Alkynylation/(
E
)‐Alkenylation: A Unified Rapid Access to α,β‐Unsaturated Ketones and Propargyl Alcohols, Asian Journal of Organic Chemistry, November 2019, Wiley,
DOI: 10.1002/ajoc.201900601.
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