What is it about?

This manuscript presents the largest cohort of patients undergoing inferior vena cava resection without reconstruction (IVC Ligation) for retroperitoneal malignancies in the published literature. We present this cohort of patients, their side effects, technique, and important considerations.

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Why is it important?

This is an important manuscript because retroperitoneal tumors involving the inferior vena cava can have significant morbidity and mortality associated with operative treatment. Although reconstruction is sometimes necessary, some patients may be able to forego it if adequate collateral blood supply is present. Avoiding reconstruction may prevent complications such as graft thrombosis and thromboembolism, as well as increased operative time and associated risks. A perceived risk of IVC ligation without reconstruction is lymphedema; however, we did not notice this as a significant or debilitating side effect in our cohort. This manuscript supports further exploration and consideration of IVC ligation without reconstruction.


This work is important as we continue to move towards personalized patient care, treatment, and surgical regiments. IVC Ligation may be the right choice in some patients.

Benjamin Schmeusser

Read the Original

This page is a summary of: Resection of retroperitoneal tumors with inferior vena cava involvement without caval reconstruction, Journal of Surgical Oncology, August 2022, Wiley,
DOI: 10.1002/jso.27052.
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