What is it about?

The current coronavirus disease 2019 (COVID-19) is dispersing rapidly, and existing data has suggested several vulnerability factors for developing a severe course of the disease. This investigation was sought to study the associations of genetic polymorphisms in tumor necrosis factors (TNFs) with COVID-19 and its mortality rate.

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Why is it important?

Our findings provided deep insights into the relationship between TNFα/TNFβ polymorphisms and severe acute respiratory syndrome coronavirus 2. Replicated studies may give scientific evidence for exploring molecular mechanisms of COVID-19 in other ethnicities.

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This page is a summary of: Association of polymorphisms in tumor necrosis factors with SARS‐CoV‐2 infection and mortality rate: A case‐control study and in silico analyses, Journal of Medical Virology, December 2021, Wiley, DOI: 10.1002/jmv.27477.
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