What is it about?
This paper describes two ultrasensitive DNA nanobiosensors involving electrostatic attraction of ruthenium cations by the anionic phosphate backbone of DNA. Incorporation of graphene and multi-walled carbon nanotubes enhanced the performance of the nanobiosensors. The nanobiosensors selectively distinguish between matched and mismatched sequences.
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Why is it important?
A neutrally charged morpholino DNA sequence is used for the first time for fabrication of DNA biosensor, with the DNA probe immobilized on the surface of reduced graphene oxide, and multi-walled carbon nanotubes modified glassy carbon electrodes through the establishment of a strong gold-sulfur linkage. The nanobiosensors enabled detection of pico-molar levels of DNA.
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This page is a summary of: Fabrication of DNA based biosensors driven by electrostatic attractions on electrodes modified with reduced graphene oxide and multi‐walled carbon nanotubes, ChemNanoMat, September 2022, Wiley, DOI: 10.1002/cnma.202200262.
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