All Stories

  1. Inhibiting Monoamine Oxidase in CNS and CVS would be a Promising Approach to Mitigating Cardiovascular Complications in Neurodegenerative Disorders

    Article • CNS & Neurological Disorders - Drug Targets, March 2024, Bentham Science Publishers

    Dr BIJO MATHEW

  2. Molecular Docking, Microwave-Assisted Synthesis, Characterization and Pharmacological Evaluation of 2,4,5-trisubstituted Imidazole’s

    Article • Current Microwave Chemistry, April 2023, Bentham Science Publishers

    Deepali Bansode, Dr BIJO MATHEW

  3. In Silico Approaches to Naturally Existing Chalcones and Flavonoids on Mao Inhibitory Action: A Boon to CNS Drug Discovery

    Article • December 2022, Bentham Science Publishers

    Leena Pappachen, Dr BIJO MATHEW

  4. Development of 2D, 3D-QSAR and Pharmacophore Modeling of Chalcones for the Inhibition of Monoamine Oxidase B

    Article • Combinatorial Chemistry & High Throughput Screening, August 2022, Bentham Science Publishers

    Dr BIJO MATHEW, RANGARAJAN T M, Dr Luciana Scotti, Marcus Tullius Scotti, PUNNOTH POONKUZHI NASEEF, MOHAMED SAHEER KURUNIYAN

  5. The Role of Mitochondrial Genes in Neurodegenerative Disorders

    Article • Current Neuropharmacology, May 2022, Bentham Science Publishers

    Seetha Harilal, Dr Md.Atiar Rahman, Dr. Athanasios Alexiou, Dr BIJO MATHEW, Rajesh Kumar

  6. Current Perspective of COVID-19 on Neurology: A Mechanistic Insight

    Article • Combinatorial Chemistry & High Throughput Screening, April 2022, Bentham Science Publishers

    Seetha Harilal, Dr BIJO MATHEW, Leena Pappachen, Rajesh Kumar

  7. Nanotechnology-based Approaches and Investigational Therapeutics against COVID-19

    Article • Current Pharmaceutical Design, April 2022, Bentham Science Publishers

    Dr BIJO MATHEW, Dr Abdur Rauf

  8. Neuroprotective Effects of Ellagic Acid in Alzheimer's Disease: Focus on Underlying Molecular Mechanisms of Therapeutic Potential

    Article • Current Pharmaceutical Design, October 2021, Bentham Science Publishers

    Dr Muhammad Ajmal Shah, Azhar Rasul, Professor HAROON N KHAN, Dr BIJO MATHEW, Prof Renald Blundell

  9. Fascinating Chemopreventive Story of Wogonin: A Chance to Hit on the Head in Cancer Treatment

    Article • Current Pharmaceutical Design, March 2021, Bentham Science Publishers

    Seetha Harilal, Dr BIJO MATHEW

  10. Dysregulation of the Gut-Brain Axis, Dysbiosis and Influence of Numerous Factors on Gut Microbiota Associated Parkinson’s Disease

    Article • Current Neuropharmacology, December 2020, Bentham Science Publishers

    Dr BIJO MATHEW, Dr Muhammad Ajmal Shah, Gagandeep kaur

  11. Exploring the Role of Aggregated Proteomes in the Pathogenesis of Alzheimer’s Disease

    Article • Current Protein and Peptide Science, December 2020, Bentham Science Publishers

    Dr BIJO MATHEW

  12. New Aspects of Monoamine Oxidase B Inhibitors: The Key Role of Halogens to Open the Golden Door

    Article • Current Medicinal Chemistry, December 2020, Bentham Science Publishers

    Dr BIJO MATHEW

  13. A Comprehensive Review of Monoamine Oxidase-A Inhibitors in their Syntheses and Potencies

    Article • Combinatorial Chemistry & High Throughput Screening, December 2020, Bentham Science Publishers

    Dr BIJO MATHEW, Nisha Abdul Rehuman

  14. Privileged Pharmacophore of FDA Approved Drugs in Combination with Chalcone Framework: A New Hope for Alzheimer’s Treatment

    Article • Combinatorial Chemistry & High Throughput Screening, December 2020, Bentham Science Publishers

    Dr BIJO MATHEW

  15. Exploring the Multifunctional Neuroprotective Promise of Rasagiline Derivatives for Multi-Dysfunctional Alzheimer’s Disease

    Article • Current Pharmaceutical Design, October 2020, Bentham Science Publishers

    Md. Tanvir Kabir, Anurag Khatkar, Dr Abdur Rauf, Dr Ghulam Md Ashraf, Dr BIJO MATHEW, Mohammad Alim, Md. Habibur Rahman

  16. Emerging Promise of Immunotherapy for Alzheimer’s Disease: A New Hope for the Development of Alzheimer’s Vaccine

    Article • Current Topics in Medicinal Chemistry, June 2020, Bentham Science Publishers

    Dr BIJO MATHEW, Dr Ghulam Md Ashraf, Md. Tanvir Kabir

  17. An Environment-friendly Synthesis of Piperonal Chalcones and Their Cytotoxic and Antioxidant Evaluation

    Article • Letters in Drug Design & Discovery, February 2020, Bentham Science Publishers

    Dr BIJO MATHEW, Monu Joy, BENCY T

  18. Ethyl Acetohydroxamate Incorporated Chalcones: Unveiling a Novel Class of Chalcones for Multitarget Monoamine Oxidase-B Inhibitors Against Alzheimer’s Disease

    Article • CNS & Neurological Disorders - Drug Targets, December 2019, Bentham Science Publishers

    Dr BIJO MATHEW, RANGARAJAN T M

  19. Anti-inflammatory effect of synthesized indole-based chalcone (2E)-3-(4-bromophenyl)-1-(1H-indol-3-yl) prop-2-en-1-one: an in vitro and in vivo studies

    Article • Immunopharmacology and Immunotoxicology, October 2019, Taylor & Francis

    Dr BIJO MATHEW

  20. Studies on the interaction between HSA and new halogenated metformin derivatives: influence of lipophilic groups in the binding ability

    Article • Journal of Biomolecular Structure and Dynamics, June 2019, Taylor & Francis

    Dr BIJO MATHEW, Monu Joy, Lakshminarayanan Balasubramanian

  21. Cholinesterase Inhibitory Activities of Selected Halogenated Thiophene Chalcones

    Article • Central Nervous System Agents in Medicinal Chemistry, March 2019, Bentham Science Publishers

    Dr Vikneswaran Murugaiyah, Dr BIJO MATHEW

  22. Dual Acting Isatin-heterocyclic Hybrids: Recent Highlights as Promising Pharmacological Agents

    Article • Letters in Drug Design & Discovery, November 2018, Bentham Science Publishers

    Mr srinubabu maddela, Dr BIJO MATHEW

  23. Virtual Combinatorial Library Design, Synthesis and In vitro Anticancer Assessment of -2-Amino-3-Cyanopyridine Derivatives

    Article • Combinatorial Chemistry & High Throughput Screening, April 2018, Bentham Science Publishers

    Dr BIJO MATHEW

  24. Structural Exploration of Synthetic Chromones as Selective MAO-B Inhibitors: A Mini Review

    Article • Combinatorial Chemistry & High Throughput Screening, October 2017, Bentham Science Publishers

    Dr BIJO MATHEW

  25. Synthetic Approaches to Various Class of Topoisomerase II Inhibitors

    Article • Mini-Reviews in Organic Chemistry, September 2017, Bentham Science Publishers

    Dr BIJO MATHEW, Monu Joy

  26. Novel HDAC8 inhibitors: A multi-computational approach

    Article • SAR and QSAR in Environmental Research, September 2017, Taylor & Francis

    Dr BIJO MATHEW, Prof.Dr. DEVADASAN VELMURUGAN

  27. Monoamine Oxidase-A: A Valid Target for the Management of Depression

    Article • July 2017, Bentham Science Publishers

    Dr BIJO MATHEW, JERAD SURESH

  28. Pyrazoline: A Promising Scaffold for the Inhibition of Monoamine Oxidase

    Article • Central Nervous System Agents in Medicinal Chemistry, February 2017, Bentham Science Publishers

    Dr BIJO MATHEW

  29. Ligand based Drug Design of New Heterocyclic Imines of GABA Analogues: A Molecular Docking Approach for the Discovery of New GABA-AT Inhibitors

    Article • Central Nervous System Agents in Medicinal Chemistry, February 2017, Bentham Science Publishers

    Dr BIJO MATHEW

  30. Discovery of Camptothecin Based Topoisomerase I Inhibitors: Identification Using an Atom Based 3D-QSAR, Pharmacophore Modeling, Virtual Screening and Molecular Docking Approach

    Article • Combinatorial Chemistry & High Throughput Screening, November 2016, Bentham Science Publishers

    Dr BIJO MATHEW

  31. Monoamine Oxidase Inhibitors: Perspective Design for the Treatment of Depression and Neurological Disorders

    Article • Current Enzyme Inhibition, July 2016, Bentham Science Publishers

    Dr BIJO MATHEW

  32. Monoamine Oxidase Inhibitory Action of Chalcones: A Mini Review

    Article • Central Nervous System Agents in Medicinal Chemistry, May 2016, Bentham Science Publishers

    Dr BIJO MATHEW

  33. Flavonoids: An Outstanding Structural Core for the Inhibition of Xanthine Oxidase Enzyme

    Article • Current Enzyme Inhibition, October 2015, Bentham Science Publishers

    Dr BIJO MATHEW

  34. Development of Fluorinated Thienylchalcones as Monoamine Oxidase-B Inhibitors: Design, Synthesis, Biological Evaluation and Molecular Docking Studies

    Article • Letters in Organic Chemistry, October 2015, Bentham Science Publishers

    Dr BIJO MATHEW

  35. Development of fluorinated methoxylated chalcones as selective monoamine oxidase-B inhibitors: Synthesis, biochemistry and molecular docking studies

    Article • Bioorganic Chemistry, October 2015, Elsevier

    Dr BIJO MATHEW

  36. Hydrazones as a Privileged Structural Linker in Antitubercular Agents: A Review

    Article • Infectious Disorders - Drug Targets, July 2015, Bentham Science Publishers

    Dr BIJO MATHEW, Mr srinubabu maddela, Dr Mohamed Jawed Ahsan

  37. Molecular Hybridization and Preclinical Evaluation of Imines From Para-substituted 4-phenyl 2-amino Thiazole Incorporated with Isatin Analogues as Antitubercular Agents

    Article • Anti-Infective Agents, May 2015, Bentham Science Publishers

    Dr BIJO MATHEW

  38. Determination of in vitro free radical scavenging and antiproliferative effect of Pennisetum alopecuroides on cultured A549 human lung cancer cells

    Article • Ancient Science of Life, January 2015, Medknow

    Dr BIJO MATHEW

  39. Plant Secondary Metabolites- Potent Inhibitors of Monoamine Oxidase Isoforms

    Article • Central Nervous System Agents in Medicinal Chemistry, November 2014, Bentham Science Publishers

    Dr BIJO MATHEW

  40. Molecular Recognisation of 3a, 4-Dihydro-3-H-Indeno [1, 2-C] Pyrazole-2- Carboxamide/Carbothioamide Anticonvulsant Analogues Towards GABA-Aminotransferase- An in Silico Approach

    Article • Central Nervous System Agents in Medicinal Chemistry, November 2014, Bentham Science Publishers

    Dr BIJO MATHEW, Dr Mohamed Jawed Ahsan

  41. Isolation of a bioactive flavonoid from Spilanthes calva D.C. in vitro xanthine oxidase assay and in silico study

    Article • Biomedicine & Preventive Nutrition, October 2014, Elsevier

    Dr BIJO MATHEW

  42. Proposed interaction of some novel antidepressant pyrazolines against monoamine oxidase isoforms. Molecular docking studies and PASS assisted in silico approach

    Article • Biomedicine & Aging Pathology, October 2014, Elsevier

    Dr BIJO MATHEW

  43. Synthesis, in silico preclinical evaluation, antidepressant potential of 5-substituted phenyl-3-(thiophen-2-yl)-4,5-dihydro-1h-pyrazole-1-carboxamides

    Article • Biomedicine & Aging Pathology, October 2014, Elsevier

    Dr BIJO MATHEW

  44. Heteroaryl chalcones: Mini review about their therapeutic voyage

    Article • Biomedicine & Preventive Nutrition, July 2014, Elsevier

    Dr BIJO MATHEW

  45. Isolation and molecular recognization of 6-prenyl apigenin towards MAO-A as the active principle of seeds of Achyranthes aspera

    Article • Biomedicine & Preventive Nutrition, July 2014, Elsevier

    Dr BIJO MATHEW

  46. Pyrazoline: A Promising Scaffold for the Inhibition of Monoamine Oxidase

    Article • Central Nervous System Agents in Medicinal Chemistry, April 2014, Bentham Science Publishers

    Dr BIJO MATHEW

  47. Hypnotic Profile of Imines from Benzimidazole Chalcones: Mechanism of Synthesis, DFT Studies and in silico Screening

    Article • Central Nervous System Agents in Medicinal Chemistry, April 2014, Bentham Science Publishers

    Dr BIJO MATHEW

  48. Design of 1-(furan-2-yl)-N-(5-substituted phenyl-1, 3, 4-thiadiazol-2-yl) methanimine derivatives as Enoyl-ACP reductase inhibitors: Synthesis, molecular docking studies and anti-tubercular activity

    Article • Bangladesh Journal of Pharmacology, May 2013, Bangladesh Journals Online (BanglaJOL)

    Dr BIJO MATHEW

  49. Discovery of some novel imines of 2-amino, 5-thio, 1,3,4-thiadiazole as mucomembranous protector. Synthesis, anti-oxidant activity and in silico PASS approach

    Article • Journal of Saudi Chemical Society, January 2013, Elsevier

    Dr BIJO MATHEW

  50. Synthesis and PASS-assisted in silico approach of some novel 2-substituted benzimidazole bearing a pyrimidine-2, 4, 6(trione) system as mucomembranous protector

    Article • Journal of Pharmacy and Bioallied Sciences, January 2013, Medknow

    Dr BIJO MATHEW

  51. Antitumour activity of 5-[(2E)-1-(1H-benzimidazol-2-yl)-3-substituted phenylprop-2-en-1-ylidene] pyrimidine-2,4,6(1H,3H,5H)-triones against Dalton’s ascitic lymphoma in mice

    Article • Medicinal Chemistry Research, December 2012, Springer Science + Business Media

    Dr BIJO MATHEW

  52. Development of novel (1-H) benzimidazole bearing pyrimidine-trione based MAO-A inhibitors: Synthesis, docking studies and antidepressant activity

    Article • Journal of Saudi Chemical Society, October 2012, Elsevier

    Dr BIJO MATHEW