All Stories

  1. p53-induced ARVCF modulates the splicing landscape and supports the tumor suppressive function of p53

    Article • Oncogene, December 2019, Springer Science + Business Media

    Dr Yasushi Sasaki, Masashi Idogawa

  2. Pathogenesis of multiple pancreatic cancers involves multicentric carcinogenesis and intrapancreatic metastasis

    Article • Cancer Science, December 2019, Wiley

    Dr Yasushi Sasaki

  3. FGFR Signaling as a Candidate Therapeutic Target for Cancers Resistant to Carbon Ion Radiotherapy

    Article • International Journal of Molecular Sciences, September 2019, MDPI AG

    Dr Yasushi Sasaki

  4. Genomic characterization for familial cases with urothelial carcinoma

    Article • International Cancer Conference Journal, June 2019, Springer Science + Business Media

    Dr Yasushi Sasaki

  5. Prognostic Effect of Long Noncoding RNA NEAT1 Expression Depends on p53 Mutation Status in Cancer

    Article • Journal of Oncology, May 2019, Hindawi Publishing Corporation

    Dr Yasushi Sasaki, Masashi Idogawa

  6. A subset of diffuse-type gastric cancer is susceptible to mTOR inhibitors and checkpoint inhibitors

    Article • Journal of Experimental & Clinical Cancer Research, March 2019, Springer Science + Business Media

    Dr Yasushi Sasaki, Dr Mikito Inokuchi

  7. Malignant paraganglioma of the posterior mediastinum: A case report with genetic analysis

    Article • Molecular and Clinical Oncology, November 2018, Spandidos Publications

    Dr Yasushi Sasaki

  8. Dysregulation of miRNA in chronic hepatitis B is associated with hepatocellular carcinoma risk after nucleos(t)ide analogue treatment

    Article • Cancer Letters, October 2018, Elsevier

    Dr Yasushi Sasaki

  9. DOT1L inhibition blocks multiple myeloma cell proliferation by suppressing IRF4-MYC signaling

    Article • Haematologica, August 2018, Ferrata Storti Foundation (Haematologica)

    Dr Yasushi Sasaki

  10. Mutational analysis of uterine cervical cancer that survived multiple rounds of radiotherapy

    Article • Oncotarget, August 2018, Impact Journals, LLC

    Dr Yasushi Sasaki

  11. Targeted next-generation sequencing of 50 cancer-related genes in Japanese patients with oral squamous cell carcinoma

    Article • Tumor Biology, August 2018, SAGE Publications

    Dr Yasushi Sasaki, Masashi Idogawa

  12. Screening for long noncoding RNAs associated with oral squamous cell carcinoma reveals the potentially oncogenic actions of DLEU1

    Article • Cell Death and Disease, August 2018, Springer Science + Business Media

    Masashi Idogawa, Dr Yasushi Sasaki

  13. Prognostic nutritional index and early mortality with percutaneous endoscopic gastrostomy

    Article • QJM, June 2018, Oxford University Press (OUP)

    Dr Yasushi Sasaki

  14. Surface microstructures are associated with mutational intratumoral heterogeneity in colorectal tumors

    Article • Journal of Gastroenterology, June 2018, Springer Science + Business Media

    Dr Yasushi Sasaki

  15. Target amplicon exome-sequencing identifies promising diagnosis and prognostic markers involved in RTK-RAS and PI3K-AKT signaling as central oncopathways in primary central nervous system lymphoma

    Article • Oncotarget, May 2018, Impact Journals, LLC

    Dr Yasushi Sasaki

  16. Impaired diversity of the lung microbiome predicts progression of idiopathic pulmonary fibrosis

    Article • February 2018, Springer Science + Business Media

    Dr Yasushi Sasaki

  17. Targeted sequencing reveals genetic variants associated with sensitivity of 79 human cancer xenografts to anticancer drugs

    Article • Experimental and Therapeutic Medicine, November 2017, Spandidos Publications

    Dr Yasushi Sasaki

  18. Identification and characterization of a metastatic suppressor BRMS1L as a target gene of p53

    Article • Cancer Science, November 2017, Wiley

    Masashi Idogawa, Dr Yasushi Sasaki

  19. Profiling cancer-related gene mutations in oral squamous cell carcinoma from Japanese patients by targeted amplicon sequencing

    Article • Oncotarget, July 2017, Impact Journals, LLC

    Masashi Idogawa, Dr Yasushi Sasaki

  20. Fledglings in p53 signaling network

    Article • Oncotarget, July 2017, Impact Journals, LLC

    Masashi Idogawa, Dr Yasushi Sasaki

  21. Assessment of the quality of DNA from various formalin-fixed paraffin-embedded (FFPE) tissues and the use of this DNA for next-generation sequencing (NGS) with no artifactual mutation

    Article • PLoS ONE, May 2017, PLOS

    Dr Yasushi Sasaki

  22. p53 mediates the suppression of cancer cell invasion by inducing LIMA1/EPLIN

    Article • Cancer Letters, April 2017, Elsevier

    Masashi Idogawa, Dr Yasushi Sasaki

  23. Long non-coding RNA NEAT1 is a transcriptional target of p53 and modulates p53-induced transactivation and tumor-suppressor function

    Article • International Journal of Cancer, March 2017, Wiley

    Masashi Idogawa, Dr Yasushi Sasaki

  24. TET1 Depletion Induces Aberrant CpG Methylation in Colorectal Cancer Cells

    Article • PLoS ONE, December 2016, PLOS

    Dr Yasushi Sasaki

  25. Systemic Prophylactic Antibiotics for the Modified Introducer Method for Percutaneous Endoscopic Gastrostomy

    Article • Journal of Clinical Gastroenterology, October 2016, Wolters Kluwer Health

    Dr Yasushi Sasaki

  26. Identification and characterization of the intercellular adhesion molecule-2 gene as a novel p53 target

    Article • Oncotarget, August 2016, Impact Journals, LLC

    Masashi Idogawa, Dr Yasushi Sasaki

  27. Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress

    Article • Oncotarget, July 2016, Impact Journals, LLC

    Dr Yasushi Sasaki

  28. The effect of forced expression of mutatedK-RASgene on gastrointestinal cancer cell lines and the IGF-1R targeting therapy

    Article • Molecular Carcinogenesis, June 2016, Wiley

    Dr Yasushi Sasaki

  29. Genomic characterization of esophageal squamous cell carcinoma: Insights from next-generation sequencing

    Article • World Journal of Gastroenterology, February 2016, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Dr Yasushi Sasaki

  30. Epigenetic silencing of NTSR1 is associated with lateral and noninvasive growth of colorectal tumors

    Article • Oncotarget, October 2015, Impact Journals, LLC

    Dr Yasushi Sasaki

  31. Molecular diagnostics of a single drug-resistant multiple myeloma case using targeted next-generation sequencing

    Article • OncoTargets and Therapy, October 2015, Dove Medical Press

    Dr Yasushi Sasaki

  32. CRKL oncogene is downregulated by p53 through miR‐200s

    Article • Cancer Science, July 2015, Wiley

    Masashi Idogawa, Dr Yasushi Sasaki

  33. Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells

    Article • Oncotarget, July 2014, Impact Journals, LLC

    Masashi Idogawa, Dr Yasushi Sasaki

  34. MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions

    Article • International Journal of Cancer, April 2014, Wiley

    Dr Yasushi Sasaki

  35. Identification and analysis of large intergenic non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53-binding sites

    Article • Human Molecular Genetics, January 2014, Oxford University Press (OUP)

    Masashi Idogawa, Dr Yasushi Sasaki

  36. Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness

    Article • Oncogene, November 2013, Springer Science + Business Media

    Masashi Idogawa, Dr Yasushi Sasaki

  37. AKR1B10, a Transcriptional Target of p53, Is Downregulated in Colorectal Cancers Associated with Poor Prognosis

    Article • Molecular Cancer Research, October 2013, American Association for Cancer Research (AACR)

    Masashi Idogawa, Dr Yasushi Sasaki

  38. The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma

    Article • Tumor Biology, September 2013, Springer Science + Business Media

    Dr Yasushi Sasaki

  39. CLCA2, a target of the p53 family, negatively regulates cancer cell migration and invasion

    Article • Cancer Biology & Therapy, December 2012, Taylor & Francis

    Masashi Idogawa, Dr Yasushi Sasaki

  40. Molecular Dissection of Premalignant Colorectal Lesions Reveals Early Onset of the CpG Island Methylator Phenotype

    Article • American Journal Of Pathology, November 2012, Elsevier

    Dr Yasushi Sasaki

  41. A novel approach to cancer treatment using structural hybrids of the p53 gene family

    Article • Cancer Gene Therapy, September 2012, Springer Science + Business Media

    Masashi Idogawa, Dr Yasushi Sasaki

  42. Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes

    Article • Cell Stress and Chaperones, July 2012, Springer Science + Business Media

    Dr Yasushi Sasaki

  43. CHFR Protein Regulates Mitotic Checkpoint by Targeting PARP-1 Protein for Ubiquitination and Degradation

    Article • Journal of Biological Chemistry, February 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Masashi Idogawa, Dr Yasushi Sasaki

  44. p53 Negatively Regulates the Hepatoma Growth Factor HDGF

    Article • Cancer Research, October 2011, American Association for Cancer Research (AACR)

    Masashi Idogawa, Dr Yasushi Sasaki

  45. Genome-wide Profiling of Chromatin Signatures Reveals Epigenetic Regulation of MicroRNA Genes in Colorectal Cancer

    Article • Cancer Research, July 2011, American Association for Cancer Research (AACR)

    Dr Yasushi Sasaki

  46. Epigenetic Alteration of DNA in Mucosal Wash Fluid Predicts Invasiveness of Colorectal Tumors

    Article • Cancer Prevention Research, May 2011, American Association for Cancer Research (AACR)

    Dr Yasushi Sasaki

  47. Identification and characterization of early growth response 2, a zinc-finger transcription factor, as a p53-regulated proapoptotic gene

    Article • International Journal of Oncology, October 2010, Spandidos Publications

    Dr Yasushi Sasaki

  48. Myogenic lineage differentiated mesenchymal stem cells enhance recovery from dextran sulfate sodium-induced colitis in the rat

    Article • Journal of Gastroenterology, September 2010, Springer Science + Business Media

    Dr Yasushi Sasaki

  49. DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae

    Article • Cancer Science, April 2010, Wiley

    Dr Yasushi Sasaki

  50. Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer

    Article • Breast Cancer Research and Treatment, October 2009, Springer Science + Business Media

    Dr Yasushi Sasaki

  51. N-Propionyl-Cysteaminylphenol-Magnetite Conjugate (NPrCAP/M) Is a Nanoparticle for the Targeted Growth Suppression of Melanoma Cells

    Article • Journal of Investigative Dermatology, September 2009, Elsevier

    Dr Yasushi Sasaki

  52. IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype

    Article • Carcinogenesis, July 2009, Oxford University Press (OUP)

    Dr Yasushi Sasaki

  53. Enhancing epithelial engraftment of rat mesenchymal stem cells restores epithelial barrier integrity

    Article • The Journal of Pathology, July 2009, Wiley

    Dr Yasushi Sasaki

  54. A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth

    Article • BMC Cancer, June 2009, Springer Science + Business Media

    Masashi Idogawa, Dr Yasushi Sasaki

  55. Genomic Screening for Genes Silenced by DNA Methylation Revealed an Association between RASD1 Inactivation and Dexamethasone Resistance in Multiple Myeloma

    Article • Clinical Cancer Research, June 2009, American Association for Cancer Research (AACR)

    Dr Yasushi Sasaki

  56. A Single Recombinant Adenovirus Expressing p53 and p21-targeting Artificial microRNAs Efficiently Induces Apoptosis in Human Cancer Cells

    Article • Clinical Cancer Research, May 2009, American Association for Cancer Research (AACR)

    Masashi Idogawa, Dr Yasushi Sasaki

  57. CHFR, a potential tumor suppressor, downregulates interleukin-8 through the inhibition of NF-κB

    Article • Oncogene, May 2009, Springer Science + Business Media

    Masashi Idogawa, Dr Yasushi Sasaki

  58. p53 Family Members Regulate the Expression of the Apolipoprotein D Gene

    Article • Journal of Biological Chemistry, November 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Masashi Idogawa, Dr Yasushi Sasaki

  59. LINE-1 Hypomethylation Is Associated with Increased CpG Island Methylation in Helicobacter pylori-Related Enlarged-Fold Gastritis

    Article • Cancer Epidemiology Biomarkers & Prevention, October 2008, American Association for Cancer Research (AACR)

    Dr Yasushi Sasaki

  60. Epigenetic Silencing of MicroRNA-34b/c and B-Cell Translocation Gene 4 Is Associated with CpG Island Methylation in Colorectal Cancer

    Article • Cancer Research, June 2008, American Association for Cancer Research (AACR)

    Dr Yasushi Sasaki

  61. Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma

    Article • Cancer Science, May 2008, Wiley

    Dr Yasushi Sasaki

  62. In vitro transformation of adult rat hepatic progenitor cells into pancreatic endocrine hormone-producing cells

    Article • Journal of Hepato-Biliary-Pancreatic Surgery, May 2008, Springer Science + Business Media

    Dr Yasushi Sasaki

  63. Histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models

    Article • Molecular Cancer Therapeutics, April 2008, American Association for Cancer Research (AACR)

    Masashi Idogawa, Dr Yasushi Sasaki

  64. Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer

    Article • Carcinogenesis, February 2008, Oxford University Press (OUP)

    Dr Yasushi Sasaki

  65. Identification of Flotillin-2, a Major Protein on Lipid Rafts, as a Novel Target of p53 Family Members

    Article • Molecular Cancer Research, February 2008, American Association for Cancer Research (AACR)

    Dr Yasushi Sasaki

  66. Gene Amplification and Overexpression of PRDM14 in Breast Cancers

    Article • Cancer Research, October 2007, American Association for Cancer Research (AACR)

    Dr Yasushi Sasaki

  67. PRDM5 Identified as a Target of Epigenetic Silencing in Colorectal and Gastric Cancer

    Article • Clinical Cancer Research, August 2007, American Association for Cancer Research (AACR)

    Dr Yasushi Sasaki

  68. Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors

    Article • Carcinogenesis, August 2007, Oxford University Press (OUP)

    Masashi Idogawa, Dr Yasushi Sasaki

  69. Antitumor effect of adenovirus-mediated p53 family gene transfer on osteosarcoma cell lines

    Article • Cancer Biology & Therapy, July 2007, Taylor & Francis

    Masashi Idogawa, Dr Yasushi Sasaki

  70. Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer

    Article • Oncogene, February 2007, Springer Science + Business Media

    Dr Yasushi Sasaki

  71. Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer

    Article • Cancer Science, January 2007, Wiley

    Dr Yasushi Sasaki

  72. Comparative Genome Analysis Identifies the Vitamin D Receptor Gene as a Direct Target of p53-Mediated Transcriptional Activation

    Article • Cancer Research, May 2006, American Association for Cancer Research (AACR)

    Dr Yasushi Sasaki

  73. Small interfering RNA-induced CHFR silencing sensitizes oral squamous cell cancer cells to microtubule inhibitors

    Article • Cancer Biology & Therapy, July 2005, Taylor & Francis

    Dr Yasushi Sasaki

  74. The Ras Effector RASSF2 Is a Novel Tumor-Suppressor Gene in Human Colorectal Cancer

    Article • Gastroenterology, July 2005, Elsevier

    Dr Yasushi Sasaki

  75. Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes

    Article • Oncogene, April 2005, Springer Science + Business Media

    Dr Yasushi Sasaki

  76. Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours

    Article • British Journal of Cancer, March 2005, Springer Science + Business Media

    Dr Yasushi Sasaki

  77. Abnormal β-catenin expression in oral cancer with no gene mutation: correlation with expression of cyclin D1 and epidermal growth factor receptor, Ki-67 labeling index, and clinicopathological features

    Article • Human Pathology, March 2005, Elsevier

    Dr Yasushi Sasaki

  78. Epigenetic inactivation of class II transactivator (CIITA) is associated with the absence of interferon-γ-induced HLA-DR expression in colorectal and gastric cancer cells

    Article • Oncogene, October 2004, Springer Science + Business Media

    Dr Yasushi Sasaki

  79. Identification of SCN3B as a novel p53-inducible proapoptotic gene

    Article • Oncogene, August 2004, Springer Science + Business Media

    Dr Yasushi Sasaki

  80. Aberrant Methylation and Histone Deacetylation Associated with Silencing of SLC5A8 in Gastric Cancer

    Article • Tumor Biology, January 2004, Springer Science + Business Media

    Dr Yasushi Sasaki

  81. Epigenetic inactivation of CHFR in human tumors

    Article • Proceedings of the National Academy of Sciences, June 2003, Proceedings of the National Academy of Sciences

    Dr Yasushi Sasaki

  82. Analysis of lung tumorigenesis in chimeric mice indicates the Pulmonary adenoma resistance 2 (Par2) locus to operate in the tumor-initiation stage in a cell-autonomous manner: detection of polymorphisms in the Polı gene as a candidate for Par2

    Article • Oncogene, April 2003, Springer Science + Business Media

    Dr Yasushi Sasaki

  83. Induction of tenascin-C by tumor-specificEWS-ETS fusion genes

    Article • Genes Chromosomes and Cancer, January 2003, Wiley

    Dr Yasushi Sasaki

  84. The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors

    Article • Oncogene, November 2002, Springer Science + Business Media

    Dr Yasushi Sasaki

  85. DNA methylation and histone deacetylation associated with silencing DAP kinase gene expression in colorectal and gastric cancers

    Article • British Journal of Cancer, June 2002, Springer Science + Business Media

    Dr Yasushi Sasaki

  86. Identification of theOsteopontin gene as a direct target of TP53

    Article • Genes Chromosomes and Cancer, January 2002, Wiley

    Dr Yasushi Sasaki

  87. Increased expression of T-fimbrin gene after DNA damage in CHO cells and inactivation of T-fimbrin by CpG methylation in human colorectal cancer cells

    Article • International Journal of Cancer, December 2001, Wiley

    Dr Yasushi Sasaki

  88. Thep53Family Member Genes Are Involved in the Notch Signal Pathway

    Article • Journal of Biological Chemistry, October 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Yasushi Sasaki

  89. Adenovirus-mediated transfer of the p53 family genes, p73 and p51/p63 induces cell cycle arrest and apoptosis in colorectal cancer cell lines: potential application to gene therapy of colorectal cancer

    Article • Gene Therapy, September 2001, Springer Science + Business Media

    Dr Yasushi Sasaki

  90. Jejunal carcinoid tumor mimicking leiomyosarcoma: preoperative diagnosis by endoscopic biopsy

    Article • Journal of Gastroenterology, January 2001, Springer Science + Business Media

    Dr Yasushi Sasaki

  91. Mutational Analysis of the β-Catenin Gene in Gastric Carcinomas

    Article • Tumor Biology, January 2001, Springer Science + Business Media

    Dr Yasushi Sasaki

  92. Identification of genes highly expressed in G2-arrested Chinese hamster ovary cells by differential display analysis

    Article • Journal of Clinical Laboratory Analysis, January 2000, Wiley

    Dr Yasushi Sasaki

  93. Subcapsular hematoma of the liver and pylethrombosis in the setting of cholestatic liver injury

    Article • Journal of Gastroenterology, November 1996, Springer Science + Business Media

    Dr Yasushi Sasaki

  94. Epigenetic inactivation of SFRP genes in oral squamous cell carcinoma

    Article • International Journal of Oncology, June 1992, Spandidos Publications

    Dr Yasushi Sasaki